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10.1007/s00018-017-2725-4

http://scihub22266oqcxt.onion/10.1007/s00018-017-2725-4
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C5852194!5852194!29222645
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suck abstract from ncbi

pmid29222645      Cell+Mol+Life+Sci 2018 ; 75 (8): 1377-91
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  • Role of the microenvironment in myeloid malignancies #MMPMID29222645
  • Goulard M; Dosquet C; Bonnet D
  • Cell Mol Life Sci 2018[]; 75 (8): 1377-91 PMID29222645show ga
  • The bone marrow microenvironment (BMM) regulates the fate of hematopoietic stem cells (HSCs) in homeostatic and pathologic conditions. In myeloid malignancies, new insights into the role of the BMM and its cellular and molecular actors in the progression of the diseases have started to emerge. In this review, we will focus on describing the major players of the HSC niche and the role of the altered niche function in myeloid malignancies, more specifically focusing on the mesenchymal stroma cell compartment.
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