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10.1186/s12929-018-0427-3

http://scihub22266oqcxt.onion/10.1186/s12929-018-0427-3
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C5851271!5851271!29534728
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suck abstract from ncbi


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pmid29534728      J+Biomed+Sci 2018 ; 25 (ä): ä
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  • Long non-coding RNA MIAT in development and disease: a new player in an old game #MMPMID29534728
  • Sun C; Huang L; Li Z; Leng K; Xu Y; Jiang X; Cui Y
  • J Biomed Sci 2018[]; 25 (ä): ä PMID29534728show ga
  • Background: Long non-coding RNAs (lncRNAs), which are a portion of non-protein-coding RNAs (ncRNAs), have manifested a paramount role in the pathophysiology of human diseases, particularly in pathogenesis and progression of disease. Main body of the abstract: Myocardial infarction associated transcript (MIAT), which was recently found to demonstrate aberrant expression in various diseases, such as myocardial infarction, schizophrenia, ischemic stroke, diabetic complications, age-related cataract and cancers, is a novel disease-related lncRNA. This work summarize current evidence regarding the biological functions and underlying mechanisms of lncRNA MIAT during disease development. Short conclusion: LncRNA MIAT likely represents a feasible cancer biomarker or therapeutic target.
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