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10.1002/acm2.12293 http://scihub22266oqcxt.onion/10.1002/acm2.12293 C5849848!5849848 !29479821     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29479821 &cmd=llinks): Failed to open stream: HTTP request failed! 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Patient-specific calibration of cone-beam computed tomography data sets for radiotherapy dose calculations and treatment plan assessment |pdf=|usr=}}{{29479821 }} gab.com Text Patient-specific calibration of cone-beam computed tomography data sets for radiotherapy dose calculations and treatment plan assessment JO: J Appl Clin Med Phys http://www.kidney.de/pget.php?&tw=1&pmid=29479821 #FOAvip PURPOSE: In this work, we propose a new method of calibrating cone beam computed tomography (CBCT) data sets for radiotherapy dose calculation and plan assessment. The motivation for this patient-specific calibration (PSC) method is to develop an efficient, robust, and accurate CBCT calibration process that is less susceptible to deformable image registration (DIR) errors. METHODS: Instead of mapping the CT numbers voxel-by-voxel with traditional DIR calibration methods, the PSC methods generates correlation plots between deformably registered planning CT and CBCT voxel values, for each image slice. A linear calibration curve specific to each slice is then obtained by least-squares fitting, and applied to the CBCT slice's voxel values. This allows each CBCT slice to be corrected using DIR without altering the patient geometry through regional DIR errors. A retrospective study was performed on 15 head-and-neck cancer patients, each having routine CBCTs and a middle-of-treatment re-planning CT (reCT). The original treatment plan was re-calculated on the patient's reCT image set (serving as the gold standard) as well as the image sets produced by voxel-to-voxel DIR, density-overriding, and the new PSC calibration methods. Dose accuracy of each calibration method was compared to the reference reCT data set using common dose-volume metrics and 3D gamma analysis. A phantom study was also performed to assess the accuracy of the DIR and PSC CBCT calibration methods compared with planning CT. RESULTS: Compared with the gold standard using reCT, the average dose metric differences were ? 1.1% for all three methods (PSC: -0.3%; DIR: -0.7%; density-override: -1.1%). The average gamma pass rates with thresholds 3%, 3 mm were also similar among the three techniques (PSC: 95.0%; DIR: 96.1%; density-override: 94.4%). CONCLUSIONS: An automated patient-specific calibration method was developed which yielded strong dosimetric agreement with the results obtained using a re-planning CT for head-and-neck patients. Twit Text FOAVip Patient-specific calibration of cone-beam computed tomography data sets for radiotherapy dose calculations and treatment plan assessment ????J Appl Clin Med Phys http://www.kidney.de/pget.php?&tw=1&pmid=29479821 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29479821 #FOAvip English Wikipedia <ref>{{Cite pmid|29479821 }}</ref> Patient-specific calibration of cone-beam computed tomography data sets for radiotherapy dose calculations and treatment plan assessment #MMPMID29479821 MacFarlane M ; Wong D ; Hoover DA ; Wong E ; Johnson C ; Battista JJ ; Chen JZ J Appl Clin Med Phys 2018[Mar]; 19 (2 ): 249-257 PMID29479821 show ga PURPOSE: In this work, we propose a new method of calibrating cone beam computed tomography (CBCT) data sets for radiotherapy dose calculation and plan assessment. The motivation for this patient-specific calibration (PSC) method is to develop an efficient, robust, and accurate CBCT calibration process that is less susceptible to deformable image registration (DIR) errors. METHODS: Instead of mapping the CT numbers voxel-by-voxel with traditional DIR calibration methods, the PSC methods generates correlation plots between deformably registered planning CT and CBCT voxel values, for each image slice. A linear calibration curve specific to each slice is then obtained by least-squares fitting, and applied to the CBCT slice's voxel values. This allows each CBCT slice to be corrected using DIR without altering the patient geometry through regional DIR errors. A retrospective study was performed on 15 head-and-neck cancer patients, each having routine CBCTs and a middle-of-treatment re-planning CT (reCT). The original treatment plan was re-calculated on the patient's reCT image set (serving as the gold standard) as well as the image sets produced by voxel-to-voxel DIR, density-overriding, and the new PSC calibration methods. Dose accuracy of each calibration method was compared to the reference reCT data set using common dose-volume metrics and 3D gamma analysis. A phantom study was also performed to assess the accuracy of the DIR and PSC CBCT calibration methods compared with planning CT. RESULTS: Compared with the gold standard using reCT, the average dose metric differences were ? 1.1% for all three methods (PSC: -0.3%; DIR: -0.7%; density-override: -1.1%). The average gamma pass rates with thresholds 3%, 3 mm were also similar among the three techniques (PSC: 95.0%; DIR: 96.1%; density-override: 94.4%). CONCLUSIONS: An automated patient-specific calibration method was developed which yielded strong dosimetric agreement with the results obtained using a re-planning CT for head-and-neck patients. |*Algorithms [MESH] |*Phantoms, Imaging [MESH] |Calibration [MESH] |Cone-Beam Computed Tomography/methods/*standards [MESH] |Head and Neck Neoplasms/*radiotherapy [MESH] |Humans [MESH] |Image Processing, Computer-Assisted/methods [MESH] |Prognosis [MESH] |Radiotherapy Dosage [MESH] |Radiotherapy Planning, Computer-Assisted/*methods [MESH] |Radiotherapy, Intensity-Modulated/*methods [MESH]Patient-specific calibration of cone-beam computed tomography data set(epmc).pdf DeepDyve Pubget Overpricing