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10.5582/irdr.2018.01013 http://scihub22266oqcxt.onion/10.5582/irdr.2018.01013 C5849618!5849618!29552438     free     free     free       Intractable+Rare+Dis+Res 2018 ; 7 (1): 1-6 Nephropedia Template TP {{tp|p=29552438|t=2018. Circular RNAs and hereditary bone diseases |pdf=|usr=}}{{29552438}} gab.com Text Circular RNAs and hereditary bone diseases JO: Intractable Rare Dis Res http://www.kidney.de/pget.php?&tw=1&pmid=29552438 #FOAvip Circular RNA (circRNA) is a non-linear form of RNA derived from exonic, intronic, and exon-intron gene regions. circRNAs are characterized by covalent closed loops, highly stable nuclease resistance, and specific expression in species and developmental stages. CircRNA molecules have been identified as playing roles in the regulation of cell transcription, transcriptional expression after translation, interactions with microRNAs, and protein coding. A high stability and tissue- and disease-specific expression allow circRNAs to serve as potential biomarkers both for diseases and prognosis. CircRNAs function in bone remodeling by directly participating in bone-related signaling pathways and by forming the circRNA-miRNA-mRNA axis. Studies have seldom reported on the low incidence of circRNAs in genetic bone disorders. The current study reviews the characteristics of circRNAs and recent research on their role in rare hereditary bone diseases. Twit Text FOAVip Circular RNAs and hereditary bone diseases ????Intractable Rare Dis Res http://www.kidney.de/pget.php?&tw=1&pmid=29552438 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29552438 #FOAvip English Wikipedia <ref>{{Cite pmid|29552438}}</ref> Circular RNAs and hereditary bone diseases #MMPMID29552438 Zhai N; Lu Y; Wang Y; Ren X; Han J Intractable Rare Dis Res 2018[Feb]; 7 (1): 1-6 PMID29552438show ga Circular RNA (circRNA) is a non-linear form of RNA derived from exonic, intronic, and exon-intron gene regions. circRNAs are characterized by covalent closed loops, highly stable nuclease resistance, and specific expression in species and developmental stages. CircRNA molecules have been identified as playing roles in the regulation of cell transcription, transcriptional expression after translation, interactions with microRNAs, and protein coding. A high stability and tissue- and disease-specific expression allow circRNAs to serve as potential biomarkers both for diseases and prognosis. CircRNAs function in bone remodeling by directly participating in bone-related signaling pathways and by forming the circRNA-miRNA-mRNA axis. Studies have seldom reported on the low incidence of circRNAs in genetic bone disorders. The current study reviews the characteristics of circRNAs and recent research on their role in rare hereditary bone diseases. äCircular RNAs and hereditary bone diseases (epmc).pdf DeepDyve Pubget Overpricing