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10.1093/cid/cix663 http://scihub22266oqcxt.onion/10.1093/cid/cix663 C5848372!5848372 !29117331     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29117331 &cmd=llinks): Failed to open stream: HTTP request failed! 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Neurodevelopmental Impairment in Children After Group B Streptococcal Disease Worldwide: Systematic Review and Meta-analyses |pdf=|usr=}}{{29117331 }} gab.com Text Neurodevelopmental Impairment in Children After Group B Streptococcal Disease Worldwide: Systematic Review and Meta-analyses JO: Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=29117331 #FOAvip BACKGROUND: Survivors of infant group B streptococcal (GBS) disease are at risk of neurodevelopmental impairment (NDI), a burden not previously systematically quantified. This is the 10th of 11 articles estimating the burden of GBS disease. Here we aimed to estimate NDI in survivors of infant GBS disease. METHODS: We conducted systematic literature reviews (PubMed/Medline, Embase, Latin American and Caribbean Health Sciences Literature [LILACS], World Health Organization Library Information System [WHOLIS], and Scopus) and sought unpublished data on the risk of NDI after invasive GBS disease in infants <90 days of age. We did meta-analyses to derive pooled estimates of the percentage of infants with NDI following GBS meningitis. RESULTS: We identified 6127 studies, of which 18 met eligibility criteria, all from middle- or high-income contexts. All 18 studies followed up survivors of GBS meningitis; only 5 of these studies also followed up survivors of GBS sepsis and were too few to pool in a meta-analysis. Of meningitis survivors, 32% (95% CI, 25%-38%) had NDI at 18 months of follow-up, including 18% (95% CI, 13%-22%) with moderate to severe NDI. CONCLUSIONS: GBS meningitis is an important risk factor for moderate to severe NDI, affecting around 1 in 5 survivors. However, data are limited, and we were unable to estimate NDI after GBS sepsis. Comparability of studies is difficult due to methodological differences including variability in timing of clinical reviews and assessment tools. Follow-up of clinical cases and standardization of methods are essential to fully quantify the total burden of NDI associated with GBS disease, and inform program priorities. Twit Text FOAVip Neurodevelopmental Impairment in Children After Group B Streptococcal Disease Worldwide: Systematic Review and Meta-analyses ????Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=29117331 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29117331 #FOAvip English Wikipedia <ref>{{Cite pmid|29117331 }}</ref> Neurodevelopmental Impairment in Children After Group B Streptococcal Disease Worldwide: Systematic Review and Meta-analyses #MMPMID29117331 Kohli-Lynch M ; Russell NJ ; Seale AC ; Dangor Z ; Tann CJ ; Baker CJ ; Bartlett L ; Cutland C ; Gravett MG ; Heath PT ; Ip M ; Le Doare K ; Madhi SA ; Rubens CE ; Saha SK ; Schrag S ; Sobanjo-Ter Meulen A ; Vekemans J ; O'Sullivan C ; Nakwa F ; Ben Hamouda H ; Soua H ; Giorgakoudi K ; Ladhani S ; Lamagni T ; Rattue H ; Trotter C ; Lawn JE Clin Infect Dis 2017[Nov]; 65 (suppl_2 ): S190-S199 PMID29117331 show ga BACKGROUND: Survivors of infant group B streptococcal (GBS) disease are at risk of neurodevelopmental impairment (NDI), a burden not previously systematically quantified. This is the 10th of 11 articles estimating the burden of GBS disease. Here we aimed to estimate NDI in survivors of infant GBS disease. METHODS: We conducted systematic literature reviews (PubMed/Medline, Embase, Latin American and Caribbean Health Sciences Literature [LILACS], World Health Organization Library Information System [WHOLIS], and Scopus) and sought unpublished data on the risk of NDI after invasive GBS disease in infants <90 days of age. We did meta-analyses to derive pooled estimates of the percentage of infants with NDI following GBS meningitis. RESULTS: We identified 6127 studies, of which 18 met eligibility criteria, all from middle- or high-income contexts. All 18 studies followed up survivors of GBS meningitis; only 5 of these studies also followed up survivors of GBS sepsis and were too few to pool in a meta-analysis. Of meningitis survivors, 32% (95% CI, 25%-38%) had NDI at 18 months of follow-up, including 18% (95% CI, 13%-22%) with moderate to severe NDI. CONCLUSIONS: GBS meningitis is an important risk factor for moderate to severe NDI, affecting around 1 in 5 survivors. However, data are limited, and we were unable to estimate NDI after GBS sepsis. Comparability of studies is difficult due to methodological differences including variability in timing of clinical reviews and assessment tools. Follow-up of clinical cases and standardization of methods are essential to fully quantify the total burden of NDI associated with GBS disease, and inform program priorities. |*Streptococcus agalactiae [MESH] |Developmental Disabilities/epidemiology/*etiology/microbiology [MESH] |Global Health/statistics & numerical data [MESH] |Humans [MESH] |Infant [MESH] |Meningitis, Bacterial/complications/epidemiology [MESH] |Risk Factors [MESH]Neurodevelopmental Impairment in Children After Group B Streptococcal (epmc).pdf DeepDyve Pubget Overpricing