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10.1007/s40472-018-0177-x http://scihub22266oqcxt.onion/10.1007/s40472-018-0177-x C5843691!5843691!29564204     free     free     free       Curr+Transplant+Rep 2018 ; 5 (1): 14-8 Nephropedia Template TP {{tp|p=29564204|t=2018. Roadblocks in the Path of iPSC to the Clinic |pdf=|usr=}}{{29564204}} gab.com Text Roadblocks in the Path of iPSC to the Clinic JO: Curr Transplant Rep http://www.kidney.de/pget.php?&tw=1&pmid=29564204 #FOAvip Purpose of Review: The goal of this paper is to highlight the major challenges in the translation of human pluripotent stem cells into a clinical setting. Recent Findings: Innate features from human induced pluripotent stem cells (hiPSCs) positioned these patient-specific cells as an unprecedented cell source for regenerative medicine applications. Immunogenicity of differentiated iPSCs requires more research towards the definition of common criteria for the evaluation of innate and host immune responses as well as in the generation of standardized protocols for iPSC generation and differentiation. The coming years will resolve ongoing clinical trials using both human embryonic stem cells (hESCs) and hiPSCs providing exciting information for the optimization of potential clinical applications of stem cell therapies. Summary: Rapid advances in the field of iPSCs generated high expectations in the field of regenerative medicine. Understanding therapeutic applications of iPSCs certainly needs further investigation on autologous/allogenic iPSC transplantation. Twit Text FOAVip Roadblocks in the Path of iPSC to the Clinic ????Curr Transplant Rep http://www.kidney.de/pget.php?&tw=1&pmid=29564204 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29564204 #FOAvip English Wikipedia <ref>{{Cite pmid|29564204}}</ref> Roadblocks in the Path of iPSC to the Clinic #MMPMID29564204 Garreta E; Sanchez S; Lajara J; Montserrat N; Belmonte JCI Curr Transplant Rep 2018[]; 5 (1): 14-8 PMID29564204show ga Purpose of Review: The goal of this paper is to highlight the major challenges in the translation of human pluripotent stem cells into a clinical setting. Recent Findings: Innate features from human induced pluripotent stem cells (hiPSCs) positioned these patient-specific cells as an unprecedented cell source for regenerative medicine applications. Immunogenicity of differentiated iPSCs requires more research towards the definition of common criteria for the evaluation of innate and host immune responses as well as in the generation of standardized protocols for iPSC generation and differentiation. The coming years will resolve ongoing clinical trials using both human embryonic stem cells (hESCs) and hiPSCs providing exciting information for the optimization of potential clinical applications of stem cell therapies. Summary: Rapid advances in the field of iPSCs generated high expectations in the field of regenerative medicine. Understanding therapeutic applications of iPSCs certainly needs further investigation on autologous/allogenic iPSC transplantation. äRoadblocks in the Path of iPSC to the Clinic (epmc).pdf DeepDyve Pubget Overpricing