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10.1136/bmjpo-2017-000013 http://scihub22266oqcxt.onion/10.1136/bmjpo-2017-000013 C5842988!5842988 !29637092     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29637092 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMJ+Paediatr+Open 2017 ; 1 (1 ): e000013 Nephropedia Template TP {{tp|p=29637092 |t=2017. Pressure-related flow rates for continuous renal replacement therapy in very small children: an in vitro study |pdf=|usr=}}{{29637092 }} gab.com Text Pressure-related flow rates for continuous renal replacement therapy in very small children: an in vitro study JO: BMJ Paediatr Open http://www.kidney.de/pget.php?&tw=1&pmid=29637092 #FOAvip OBJECTIVE: Continuous renal replacement therapy (CRRT) is extremely challenging in very small children, as most CRRT intravascular access devices are too large. We aimed to quantify flow rates through several alternative intravascular devices. DESIGN: Experimental in vitro study simulating CRRT. SETTING: Whole milk and equine blood were used as human blood substitutes due to similar viscosity. Milk under gravity pressure was run through a standard CRRT circuit. Equine blood was run through a working CRRT machine. SUBJECTS: Eight intravenous access devices used in paediatrics, with a variety of connectors. INTERVENTIONS: Devices were tested with milk for flow between 50 and 200?mm Hg pressure, and with blood for pressure at flows between 20 and 50?mL/min. MAIN OUTCOME MEASURES: Flows at each input pressure with milk, and pressures at each flow rate with blood. RESULTS: With both experimental systems, 8Fr and 6.5Fr haemodialysis catheters, and 18G and 20G cannulae allowed excellent low pressure flow rates. 5Fr triple central catheter, 5Fr and 4Fr umbilical venous catheter, and 5Fr haemodialysis catheters did not allow flows at reasonable pressures for CRRT. A three-way tap did not impede flows, but a needle-free valve did. Flows increased with pressure non-linearly, presumably due to increasing turbulence. CONCLUSIONS: In very small patients needing CRRT, where large haemodialysis catheters cannot be used due to the patient size, we advise the use of two 18G cannulae in different sites. A three-way tap can be added, but not any other connectors. In vitro this system gave suitable flow rates with some flexibility for in vivo variations. Twit Text FOAVip Pressure-related flow rates for continuous renal replacement therapy in very small children: an in vitro study ????BMJ Paediatr Open http://www.kidney.de/pget.php?&tw=1&pmid=29637092 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29637092 #FOAvip English Wikipedia <ref>{{Cite pmid|29637092 }}</ref> Pressure-related flow rates for continuous renal replacement therapy in very small children: an in vitro study #MMPMID29637092 Stevens-Harris I ; Raffaj D ; Davies P BMJ Paediatr Open 2017[]; 1 (1 ): e000013 PMID29637092 show ga OBJECTIVE: Continuous renal replacement therapy (CRRT) is extremely challenging in very small children, as most CRRT intravascular access devices are too large. We aimed to quantify flow rates through several alternative intravascular devices. DESIGN: Experimental in vitro study simulating CRRT. SETTING: Whole milk and equine blood were used as human blood substitutes due to similar viscosity. Milk under gravity pressure was run through a standard CRRT circuit. Equine blood was run through a working CRRT machine. SUBJECTS: Eight intravenous access devices used in paediatrics, with a variety of connectors. INTERVENTIONS: Devices were tested with milk for flow between 50 and 200?mm Hg pressure, and with blood for pressure at flows between 20 and 50?mL/min. MAIN OUTCOME MEASURES: Flows at each input pressure with milk, and pressures at each flow rate with blood. RESULTS: With both experimental systems, 8Fr and 6.5Fr haemodialysis catheters, and 18G and 20G cannulae allowed excellent low pressure flow rates. 5Fr triple central catheter, 5Fr and 4Fr umbilical venous catheter, and 5Fr haemodialysis catheters did not allow flows at reasonable pressures for CRRT. A three-way tap did not impede flows, but a needle-free valve did. Flows increased with pressure non-linearly, presumably due to increasing turbulence. CONCLUSIONS: In very small patients needing CRRT, where large haemodialysis catheters cannot be used due to the patient size, we advise the use of two 18G cannulae in different sites. A three-way tap can be added, but not any other connectors. In vitro this system gave suitable flow rates with some flexibility for in vivo variations. äPressure-related flow rates for continuous renal replacement therapy i(epmc).pdf DeepDyve Pubget Overpricing