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10.3238/arztebl.2018.0106 http://scihub22266oqcxt.onion/10.3238/arztebl.2018.0106 C5842342!5842342!29510820     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dtsch+Arztebl+Int 2018 ; 115 (7): 106-11 Nephropedia Template TP {{tp|p=29510820|t=2018. The Interdisciplinary Diagnosis and Treatment of Intraocular Tumors |pdf=|usr=}}{{29510820}} gab.com Text The Interdisciplinary Diagnosis and Treatment of Intraocular Tumors JO: Dtsch Arztebl Int http://www.kidney.de/pget.php?&tw=1&pmid=29510820 #FOAvip Background: Recent years have seen major changes in the diagnosis and treatment of solid intraocular tumors, mainly owing to an improved molecular biological understanding of their pathogenesis, new therapeutic approaches for the local treatment of tumors in children, and long-term follow-up observations in clinical trials. Methods: This review is based on pertinent publications retrieved by a selective search in PubMed. Results: Retinoblastoma is the most common type of primary intraocular tumor, with approximately 8000 new cases per year around the world, while malignant melanoma of the uvea is the most common primary intraocular tumor in adults, with approximately 7000 new cases per year around the world. Intraocular metastases of malignant tumors are ten times more common, in terms of incidence, than primary intraocular tumors and are therefore the most common intraocular tumors overall. Improved methods of intraocular biopsy, diagnostic imaging, and molecular genetic investigation have led to steady improvement in clinical and predictive diagnostic assessment. In the treatment of retinoblastoma, local techniques including brachytherapy and intra-arterial and intravitreal chemotherapy play a prominent role. Prognostic molecular-genetic testing now enables the highly selective identification of uveal melanomas that have a high potential to metastasize. Cutaneous and uveal melanomas differ both in their clinical behavior and in their basic biological features; to date, effective systemic treatment has been established for melanoma of the skin, but not for metastatic melanoma of the uvea. Intraocular metastases are common and often the initial manifestation of an extraocular tumor, particularly lung cancer. Conclusion: Modern diagnostic and therapeutic concepts for intraocular tumors can only be implemented through the close interdisciplinary collaboration of ophthalmologists, oncologists, radiologists, radiotherapists, pathologists, and human geneticists. Twit Text FOAVip The Interdisciplinary Diagnosis and Treatment of Intraocular Tumors ????Dtsch Arztebl Int http://www.kidney.de/pget.php?&tw=1&pmid=29510820 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29510820 #FOAvip English Wikipedia <ref>{{Cite pmid|29510820}}</ref> The Interdisciplinary Diagnosis and Treatment of Intraocular Tumors #MMPMID29510820 Bornfeld N; Biewald E; Bauer S; Temming P; Lohmann D; Zeschnigk M Dtsch Arztebl Int 2018[Feb]; 115 (7): 106-11 PMID29510820show ga Background: Recent years have seen major changes in the diagnosis and treatment of solid intraocular tumors, mainly owing to an improved molecular biological understanding of their pathogenesis, new therapeutic approaches for the local treatment of tumors in children, and long-term follow-up observations in clinical trials. Methods: This review is based on pertinent publications retrieved by a selective search in PubMed. Results: Retinoblastoma is the most common type of primary intraocular tumor, with approximately 8000 new cases per year around the world, while malignant melanoma of the uvea is the most common primary intraocular tumor in adults, with approximately 7000 new cases per year around the world. Intraocular metastases of malignant tumors are ten times more common, in terms of incidence, than primary intraocular tumors and are therefore the most common intraocular tumors overall. Improved methods of intraocular biopsy, diagnostic imaging, and molecular genetic investigation have led to steady improvement in clinical and predictive diagnostic assessment. In the treatment of retinoblastoma, local techniques including brachytherapy and intra-arterial and intravitreal chemotherapy play a prominent role. Prognostic molecular-genetic testing now enables the highly selective identification of uveal melanomas that have a high potential to metastasize. Cutaneous and uveal melanomas differ both in their clinical behavior and in their basic biological features; to date, effective systemic treatment has been established for melanoma of the skin, but not for metastatic melanoma of the uvea. Intraocular metastases are common and often the initial manifestation of an extraocular tumor, particularly lung cancer. Conclusion: Modern diagnostic and therapeutic concepts for intraocular tumors can only be implemented through the close interdisciplinary collaboration of ophthalmologists, oncologists, radiologists, radiotherapists, pathologists, and human geneticists. äThe Interdisciplinary Diagnosis and Treatment of Intraocular Tumors (epmc).pdf DeepDyve Pubget Overpricing