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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Medicine+(Baltimore)
2018 ; 97
(8
): e9889
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Nitrite-induced acute kidney injury with secondary hyperparathyroidism: Case
report and literature review
#MMPMID29465577
Peng T
; Hu Z
; Yang X
; Gao Y
; Ma C
Medicine (Baltimore)
2018[Feb]; 97
(8
): e9889
PMID29465577
show ga
RATIONALE: Acute kidney injury (AKI) with hyperparathyroidism caused by nitrite
was rare, and renal function and parathyroid hormone (PTH) decreased to normal
range after therapy. PATIENT CONCERNS: Acute kidney injury was diagnosed in a
40-year-old male with hyperparathyroidism and cyanosis of his hands and both
forearms. DIAGNOSES: The patient ate some recently pickled vegetables, and he
experienced nausea, vomiting and diarrhoea without oliguria or anuria;
Additionally, his hands and both forearms had a typical blue ash appearance.
After admission, the laboratory findings indicated theincreasing serum creatinine
(Scr) and parathyroid hormone (PTH). He was diagnosed as acute kidney injury with
hyperparathyroidism caused by nitrite. INTERVENTIONS: The patient stopped eating
the pickled vegetables and was given rehydration, added calories and other
supportive therapy without any glucocorticoids. OUTCOMES: According to his
clinical manifestations, laboratory findings and imaging results, the patient was
diagnosed with acute kidney injury with secondary hyperparathyroidism. He was
given symptomatic supportive care therapy. After one week, the serum creatinine,
parathyroid hormone (PTH), hypercalcemia, hyperphosphatemia, proteinuria, and
urine red blood cell values decreased to normal range. LESSONS: Nitrite-induced
acute kidney injury with secondary hyperparathyroidism was relatively rare. After
therapy, the function of the kidney and parathyroid returned to normal. This case
suggests that detailed collection of medical history, physical examination and
correct symptomatic treatment is very important.