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10.1371/journal.pone.0193088 http://scihub22266oqcxt.onion/10.1371/journal.pone.0193088 C5841737!5841737 !29513684     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29513684 &cmd=llinks): Failed to open stream: HTTP request failed! 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Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials gov and the European Union Clinical Trials Register |pdf=|usr=}}{{29513684 }} gab.com Text Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials gov and the European Union Clinical Trials Register JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=29513684 #FOAvip OBJECTIVE: Trial registries are a key source of information for clinicians and researchers. While building OpenTrials, an open database of public trial information, we identified errors and omissions in registries, including discrepancies between descriptions of the same trial in different registries. We set out to ascertain the prevalence of discrepancies in trial completion status using a cohort of trials registered on both the European Union Clinical Trials Register (EUCTR) and ClinicalTrials.gov. STUDY DESIGN AND SETTING: We used matching titles and registry IDs provided by both registries to build a cohort of dual-registered trials. Completion statuses were compared; we calculated descriptive statistics on the prevalence of discrepancies. RESULTS: 11,988 dual-registered trials were identified. 1,496 did not provide a comparable completion status, leaving 10,492 trials. 16.2% were discrepant on completion status. The majority of discrepancies (90.5%) were a 'completed' trial on ClinicalTrials.gov inaccurately marked as 'ongoing' on EUCTR. Overall, 33.9% of dual-registered trials described as 'ongoing' on EUCTR were listed as 'completed' on ClinicalTrials.gov. CONCLUSION: Completion status on registries is commonly inaccurate. Previous work on publication bias may underestimate non-reporting. We describe simple steps registry owners and trialists could take to improve accuracy. Twit Text FOAVip Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials gov and the European Union Clinical Trials Register ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=29513684 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29513684 #FOAvip English Wikipedia <ref>{{Cite pmid|29513684 }}</ref> Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials gov and the European Union Clinical Trials Register #MMPMID29513684 Fleminger J ; Goldacre B PLoS One 2018[]; 13 (3 ): e0193088 PMID29513684 show ga OBJECTIVE: Trial registries are a key source of information for clinicians and researchers. While building OpenTrials, an open database of public trial information, we identified errors and omissions in registries, including discrepancies between descriptions of the same trial in different registries. We set out to ascertain the prevalence of discrepancies in trial completion status using a cohort of trials registered on both the European Union Clinical Trials Register (EUCTR) and ClinicalTrials.gov. STUDY DESIGN AND SETTING: We used matching titles and registry IDs provided by both registries to build a cohort of dual-registered trials. Completion statuses were compared; we calculated descriptive statistics on the prevalence of discrepancies. RESULTS: 11,988 dual-registered trials were identified. 1,496 did not provide a comparable completion status, leaving 10,492 trials. 16.2% were discrepant on completion status. The majority of discrepancies (90.5%) were a 'completed' trial on ClinicalTrials.gov inaccurately marked as 'ongoing' on EUCTR. Overall, 33.9% of dual-registered trials described as 'ongoing' on EUCTR were listed as 'completed' on ClinicalTrials.gov. CONCLUSION: Completion status on registries is commonly inaccurate. Previous work on publication bias may underestimate non-reporting. We describe simple steps registry owners and trialists could take to improve accuracy. |*Bias [MESH] |Clinical Trials as Topic/*statistics & numerical data [MESH] |Cohort Studies [MESH] |Cross-Sectional Studies [MESH] |Databases, Factual/*statistics & numerical data [MESH] |Europe/epidemiology [MESH] |European Union [MESH] |Humans [MESH] |Prevalence [MESH] |Registries/*statistics & numerical data [MESH]Prevalence of clinical trial status discrepancies: A cross-sectional s(epmc).pdf DeepDyve Pubget Overpricing