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Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Exp+Ther+Med 2018 ; 15 (4): 3169-72 Nephropedia Template TP
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Recurrent primary hyperoxaluria type 2 leads to early post-transplant renal function loss: A case report #MMPMID29545831
Liu S; Gao B; Wang G; Wang W; Lian X; Wu S; Yu J; Fu Y; Zhou H
Exp Ther Med 2018[Apr]; 15 (4): 3169-72 PMID29545831show ga
Primary hyperoxaluria type 2 is a rare autosomal recessive disorder caused by glyoxylate reductase/hydroxypyruvate reductase deficiency and characterized by recurrent episodes of nephrolithiasis and nephrocalcinosis. Herein, we describe a case of primary hyperoxaluria type 2 in a 33-year-old man who failed to respond to conventional therapies; thus renal transplantation was performed. This case demonstrated that, although primary hyperoxaluria type 2 is rare, hyperoxaluria should be suspected and blood oxalate and stone component be examined in patients with recurrent episodes of nephrolithiasis, particularly in those who are unresponsive to conventional therapies. Combined liver-kidney transplant may be required as kidney transplant alone is not likely to be successful.