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10.1186/s12894-018-0328-5 http://scihub22266oqcxt.onion/10.1186/s12894-018-0328-5 C5840788!5840788!29510690     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Urol 2018 ; 18 (ä): ä Nephropedia Template TP {{tp|p=29510690|t=2018. Mannitol reduces nephron loss after warm renal ischemia in a porcine model |pdf=|usr=}}{{29510690}} gab.com Text Mannitol reduces nephron loss after warm renal ischemia in a porcine model JO: BMC Urol http://www.kidney.de/pget.php?&tw=1&pmid=29510690 #FOAvip Background: Mannitol has been employed to ameliorate renal warm ischemia damage during partial nephrectomy, however, there is limited scientific evidence to support the use of mannitol during partial nephrectomy. The objective of the present study was to investigate the glomerular number after renal warm ischemia, with and without the use of mannitol in a Pig Model. Methods: Twenty-four male pigs were assigned into three groups. Eight animals were allocated to the sham group that was subjected to laparoscopic dissection of the left renal hilum, without renal ischemia. Eight animals were allocated to the ischemia group that had the left renal hilum clamped for 30 min through laparoscopic access. Eight animals received mannitol (250 mg/kg) before the occlusion of renal hilum for 30 min. The kidneys were collected after the euthanasia of the pigs 21 days post surgery. The right kidney was utilized as a self-control for each animal. Serum creatinine, urea levels, the weight and volume of the kidneys were measured. Glomerular volumetric density, volume-weighted glomerular volume, and cortical volume were quantified through stereological methods and employed to determine the number of nephrons per kidney. Student?s t test and ANOVA were used for statistical analysis. Results: In the ischemia group, the left kidney recorded a reduction of 24.6% (290, 000 glomeruli) in the number of glomeruli in comparison to the right kidney. Kidneys subjected to ischemia also displayed decreased weight and volume in comparison to the sham and mannitol groups. No difference was observed between the left and right kidneys from the sham and mannitol groups. Further, no distinction in serum creatinine and urea among the groups was observed. Conclusion: The use of mannitol significantly reduces nephron loss during warm ischemia in pigs. Twit Text FOAVip Mannitol reduces nephron loss after warm renal ischemia in a porcine model ????BMC Urol http://www.kidney.de/pget.php?&tw=1&pmid=29510690 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29510690 #FOAvip English Wikipedia <ref>{{Cite pmid|29510690}}</ref> Mannitol reduces nephron loss after warm renal ischemia in a porcine model #MMPMID29510690 Damasceno-Ferreira JA; Abreu LAS; Bechara GR; Costa WS; Pereira-Sampaio MA; Sampaio FJB; De Souza DB BMC Urol 2018[]; 18 (ä): ä PMID29510690show ga Background: Mannitol has been employed to ameliorate renal warm ischemia damage during partial nephrectomy, however, there is limited scientific evidence to support the use of mannitol during partial nephrectomy. The objective of the present study was to investigate the glomerular number after renal warm ischemia, with and without the use of mannitol in a Pig Model. Methods: Twenty-four male pigs were assigned into three groups. Eight animals were allocated to the sham group that was subjected to laparoscopic dissection of the left renal hilum, without renal ischemia. Eight animals were allocated to the ischemia group that had the left renal hilum clamped for 30 min through laparoscopic access. Eight animals received mannitol (250 mg/kg) before the occlusion of renal hilum for 30 min. The kidneys were collected after the euthanasia of the pigs 21 days post surgery. The right kidney was utilized as a self-control for each animal. Serum creatinine, urea levels, the weight and volume of the kidneys were measured. Glomerular volumetric density, volume-weighted glomerular volume, and cortical volume were quantified through stereological methods and employed to determine the number of nephrons per kidney. Student?s t test and ANOVA were used for statistical analysis. Results: In the ischemia group, the left kidney recorded a reduction of 24.6% (290, 000 glomeruli) in the number of glomeruli in comparison to the right kidney. Kidneys subjected to ischemia also displayed decreased weight and volume in comparison to the sham and mannitol groups. No difference was observed between the left and right kidneys from the sham and mannitol groups. Further, no distinction in serum creatinine and urea among the groups was observed. Conclusion: The use of mannitol significantly reduces nephron loss during warm ischemia in pigs. äMannitol reduces nephron loss after warm renal ischemia in a porcine m(epmc).pdf DeepDyve Pubget Overpricing