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10.3892/ol.2018.7982 http://scihub22266oqcxt.onion/10.3892/ol.2018.7982 C5840652!5840652!29552110     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncol+Lett 2018 ; 15 (4): 4711-9 Nephropedia Template TP {{tp|p=29552110|t=2018. Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy |pdf=|usr=}}{{29552110}} gab.com Text Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy JO: Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=29552110 #FOAvip Interleukin (IL)-37, a new IL-1 family member, has received increasing attention in recent years. In the past decade, it has been determined that IL-37 is expressed in various normal cells and tissues and is regulated by inflammatory stimuli and pro-cytokines via different signal transduction pathways. Recently, it has been found that IL-37 is expressed in a variety of cancers, chronic inflammatory and autoimmune disorders, and exerts anti-inflammatory effects. Moreover, a growing body of literature demonstrates that IL-37 plays a vital role in inhibiting both innate and adaptive immune responses as well as inflammatory reactions. In addition, IL-37 may prove to be a new and potentially useful target for effective cytokine therapy. Further evidence is needed to clarify in more detail the effects of IL-37 in experimental and clinical studies. Based on an extensive summary of published data, the aim of this review is to outline the current knowledge of IL-37, including the location, structure, expression, regulation and function, as well as the potential clinical applications of this cytokine. Twit Text FOAVip Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy ????Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=29552110 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29552110 #FOAvip English Wikipedia <ref>{{Cite pmid|29552110}}</ref> Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy #MMPMID29552110 Wang L; Quan Y; Yue Y; Heng X; Che F Oncol Lett 2018[Apr]; 15 (4): 4711-9 PMID29552110show ga Interleukin (IL)-37, a new IL-1 family member, has received increasing attention in recent years. In the past decade, it has been determined that IL-37 is expressed in various normal cells and tissues and is regulated by inflammatory stimuli and pro-cytokines via different signal transduction pathways. Recently, it has been found that IL-37 is expressed in a variety of cancers, chronic inflammatory and autoimmune disorders, and exerts anti-inflammatory effects. Moreover, a growing body of literature demonstrates that IL-37 plays a vital role in inhibiting both innate and adaptive immune responses as well as inflammatory reactions. In addition, IL-37 may prove to be a new and potentially useful target for effective cytokine therapy. Further evidence is needed to clarify in more detail the effects of IL-37 in experimental and clinical studies. Based on an extensive summary of published data, the aim of this review is to outline the current knowledge of IL-37, including the location, structure, expression, regulation and function, as well as the potential clinical applications of this cytokine. äInterleukin-37: A crucial cytokine with multiple roles in disease and (epmc).pdf DeepDyve Pubget Overpricing