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10.1084/jem.20171738

http://scihub22266oqcxt.onion/10.1084/jem.20171738
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C5839764!5839764!29374026
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suck abstract from ncbi


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pmid29374026      J+Exp+Med 2018 ; 215 (3): 761-71
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  • A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets #MMPMID29374026
  • Álvarez-Prado ÁF; Pérez-Durán P; Pérez-García A; Benguria A; Torroja C; de Yébenes VG; Ramiro AR
  • J Exp Med 2018[Mar]; 215 (3): 761-71 PMID29374026show ga
  • Álvarez-Prado et al. report a detailed map of AID-induced off-target mutations and identify molecular features that predict gene mutability. They identify a novel AID hotspot and demonstrate that base excision and mismatch repair back up each other to repair most AID deamination events.
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