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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Exp+Clin+Cancer+Res
2018 ; 37
(1
): 47
Nephropedia Template TP
gab.com Text
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Tearing down the walls: FDA approves next generation sequencing (NGS) assays for
actionable cancer genomic aberrations
#MMPMID29506529
Allegretti M
; Fabi A
; Buglioni S
; Martayan A
; Conti L
; Pescarmona E
; Ciliberto G
; Giacomini P
J Exp Clin Cancer Res
2018[Mar]; 37
(1
): 47
PMID29506529
show ga
The United States Food and Drug Administration (FDA) recently approved the
clinical use of two comprehensive 'mid-size' Next Generation Sequencing (NGS)
panels calling actionable genomic aberrations in cancer. This is the first
endorsement, by a regulatory body, of a new standard of care in oncology. Herein,
we argue that besides its many practice-changing implications, this approval
tears down the conceptual walls dividing system biology from clinical practice,
diagnosis from research, prevention from therapy, cancer genetics from cancer
genomics, and computational biology from empirical therapy assignment.