Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1159/000485242 http://scihub22266oqcxt.onion/10.1159/000485242 C5836159!5836159!29515400     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Case+Rep+Oncol 2017 ; 10 (3): 1085-91 Nephropedia Template TP {{tp|p=29515400|t=2017. Lactic Acidosis in Prostate Cancer: Consider the Warburg Effect |pdf=|usr=}}{{29515400}} gab.com Text Lactic Acidosis in Prostate Cancer: Consider the Warburg Effect JO: Case Rep Oncol http://www.kidney.de/pget.php?&tw=1&pmid=29515400 #FOAvip Lactic acidosis is a commonly observed clinical condition that is associated with a poor prognosis, especially in malignancies. We describe a case of an 81-year-old patient who presented with symptoms of tachypnea and general discomfort. Arterial blood gas analysis showed a high anion gap acidosis with a lactate level of 9.5 mmol/L with respiratory compensation. CT scanning showed no signs of pulmonary embolism or other causes of impaired tissue oxygenation. Despite treatment with sodium bicarbonate, the patient developed an adrenalin-resistant cardiac arrest, most likely caused by the acidosis. Autopsy revealed Gleason score 5 + 5 metastatic prostate cancer as the most probable cause of the lactic acidosis. Next-generation sequencing indicated a nonsense mutation in the TP53 gene (887delA) and an activating mutation in the PIK3CA gene (1634A>G) as candidate molecular drivers. This case demonstrates the prevalence and clinical relevance of metabolic reprogramming, frequently referred to as ?the Warburg effect,? in patients with prostate cancer. Twit Text FOAVip Lactic Acidosis in Prostate Cancer: Consider the Warburg Effect ????Case Rep Oncol http://www.kidney.de/pget.php?&tw=1&pmid=29515400 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29515400 #FOAvip English Wikipedia <ref>{{Cite pmid|29515400}}</ref> Lactic Acidosis in Prostate Cancer: Consider the Warburg Effect #MMPMID29515400 van der Mijn JC; Kuiper MJ; Siegert CE; Wassenaar AE; van Noesel CJ; Ogilvie AC Case Rep Oncol 2017[Sep]; 10 (3): 1085-91 PMID29515400show ga Lactic acidosis is a commonly observed clinical condition that is associated with a poor prognosis, especially in malignancies. We describe a case of an 81-year-old patient who presented with symptoms of tachypnea and general discomfort. Arterial blood gas analysis showed a high anion gap acidosis with a lactate level of 9.5 mmol/L with respiratory compensation. CT scanning showed no signs of pulmonary embolism or other causes of impaired tissue oxygenation. Despite treatment with sodium bicarbonate, the patient developed an adrenalin-resistant cardiac arrest, most likely caused by the acidosis. Autopsy revealed Gleason score 5 + 5 metastatic prostate cancer as the most probable cause of the lactic acidosis. Next-generation sequencing indicated a nonsense mutation in the TP53 gene (887delA) and an activating mutation in the PIK3CA gene (1634A>G) as candidate molecular drivers. This case demonstrates the prevalence and clinical relevance of metabolic reprogramming, frequently referred to as ?the Warburg effect,? in patients with prostate cancer. äLactic Acidosis in Prostate Cancer: Consider the Warburg Effect (epmc).pdf DeepDyve Pubget Overpricing