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10.3389/fimmu.2018.00386 http://scihub22266oqcxt.onion/10.3389/fimmu.2018.00386 C5835758!5835758!29541076     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2018 ; 9 (ä): ä Nephropedia Template TP {{tp|p=29541076|t=2018. The Role of Mast Cells in Autoimmune Bullous Dermatoses |pdf=|usr=}}{{29541076}} gab.com Text The Role of Mast Cells in Autoimmune Bullous Dermatoses JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29541076 #FOAvip Skin mast cells (MCs), a resident immune cell type with broad regulatory capacity, play an important role in sensing danger signals as well as in the control of the local immune response. It is conceivable to expect that skin MCs regulate autoimmune response and are thus involved in autoimmune diseases in the skin, e.g., autoimmune bullous dermatoses (AIBD). Therefore, exploring the role of MCs in AIBD will improve our understanding of the disease pathogenesis and the search for novel therapeutic targets. Previously, in clinical studies with AIBD, particularly bullous pemphigoid, patients? samples have demonstrated that MCs are likely involved in the development of the diseases. However, using MC-deficient mice, studies with mouse models of AIBD have obtained inconclusive or even discrepant results. Therefore, it is necessary to clarify the observed discrepancies and to elucidate the role of MCs in AIBD. Here, in this review, we aim to clarify discrepant findings and finally elucidate the role of MCs in AIBD by summarizing and discussing the findings in both clinical and experimental studies. Twit Text FOAVip The Role of Mast Cells in Autoimmune Bullous Dermatoses ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29541076 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29541076 #FOAvip English Wikipedia <ref>{{Cite pmid|29541076}}</ref> The Role of Mast Cells in Autoimmune Bullous Dermatoses #MMPMID29541076 Yu X; Kasprick A; Hartmann K; Petersen F Front Immunol 2018[]; 9 (ä): ä PMID29541076show ga Skin mast cells (MCs), a resident immune cell type with broad regulatory capacity, play an important role in sensing danger signals as well as in the control of the local immune response. It is conceivable to expect that skin MCs regulate autoimmune response and are thus involved in autoimmune diseases in the skin, e.g., autoimmune bullous dermatoses (AIBD). Therefore, exploring the role of MCs in AIBD will improve our understanding of the disease pathogenesis and the search for novel therapeutic targets. Previously, in clinical studies with AIBD, particularly bullous pemphigoid, patients? samples have demonstrated that MCs are likely involved in the development of the diseases. However, using MC-deficient mice, studies with mouse models of AIBD have obtained inconclusive or even discrepant results. Therefore, it is necessary to clarify the observed discrepancies and to elucidate the role of MCs in AIBD. Here, in this review, we aim to clarify discrepant findings and finally elucidate the role of MCs in AIBD by summarizing and discussing the findings in both clinical and experimental studies. äThe Role of Mast Cells in Autoimmune Bullous Dermatoses (epmc).pdf DeepDyve Pubget Overpricing