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10.1007/s10067-017-3698-2 http://scihub22266oqcxt.onion/10.1007/s10067-017-3698-2 C5835059!5835059!28593610     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28593610&cmd=llinks): Failed to open stream: HTTP request failed! 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Brief report: Decreased expression of CD244 (SLAMF4) on monocytes and platelets in patients with systemic lupus erythematosus |pdf=|usr=}}{{28593610}} gab.com Text Brief report: Decreased expression of CD244 (SLAMF4) on monocytes and platelets in patients with systemic lupus erythematosus JO: Clin Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=28593610 #FOAvip The signalling lymphocyte activation molecule (SLAM) family receptors play important roles in modulating immune responses. Previous studies in murine models and patients have suggested an association of the SLAM family (SLAMF) members with the development of autoimmunity, particularly systemic lupus erythematosus (SLE). Since previous investigations on CD244 expression have focussed on NK and T cells, the aim of this study was to evaluate the surface expression of major SLAMF members across monocytes and polymorphonuclear cells in an Asian SLE cohort and explore their potential associations with SLE-related disease activity and autoantibodies. Thirty-nine SLE patients and twenty-nine healthy controls (HC) were evaluated for the expression of CD150, CD84, CD229, CD48, CD244, CD352 and CD319. We determined a significantly lower expression of CD244 on monocytes in SLE patients compared to HC. Furthermore, monocyte CD244 expression was negatively associated with several serum autoantibody titres. Our findings suggest that this molecule plays an important role in immune tolerance mechanisms and should be investigated further.Electronic supplementary material: The online version of this article (doi:10.1007/s10067-017-3698-2) contains supplementary material, which is available to authorized users. Twit Text FOAVip Brief report: Decreased expression of CD244 (SLAMF4) on monocytes and platelets in patients with systemic lupus erythematosus ????Clin Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=28593610 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28593610 #FOAvip English Wikipedia <ref>{{Cite pmid|28593610}}</ref> Brief report: Decreased expression of CD244 (SLAMF4) on monocytes and platelets in patients with systemic lupus erythematosus #MMPMID28593610 Mak A; Thornhill SI; Lee HY; Lee B; Poidinger M; Connolly JE; Fairhurst AM Clin Rheumatol 2018[]; 37 (3): 811-6 PMID28593610show ga The signalling lymphocyte activation molecule (SLAM) family receptors play important roles in modulating immune responses. Previous studies in murine models and patients have suggested an association of the SLAM family (SLAMF) members with the development of autoimmunity, particularly systemic lupus erythematosus (SLE). Since previous investigations on CD244 expression have focussed on NK and T cells, the aim of this study was to evaluate the surface expression of major SLAMF members across monocytes and polymorphonuclear cells in an Asian SLE cohort and explore their potential associations with SLE-related disease activity and autoantibodies. Thirty-nine SLE patients and twenty-nine healthy controls (HC) were evaluated for the expression of CD150, CD84, CD229, CD48, CD244, CD352 and CD319. We determined a significantly lower expression of CD244 on monocytes in SLE patients compared to HC. Furthermore, monocyte CD244 expression was negatively associated with several serum autoantibody titres. Our findings suggest that this molecule plays an important role in immune tolerance mechanisms and should be investigated further.Electronic supplementary material: The online version of this article (doi:10.1007/s10067-017-3698-2) contains supplementary material, which is available to authorized users. äBrief report: Decreased expression of CD244 (SLAMF4) on monocytes and (epmc).pdf DeepDyve Pubget Overpricing