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10.1038/nrd.2016.117 http://scihub22266oqcxt.onion/10.1038/nrd.2016.117 C5831170!5831170!27444227     free     free     free       Nat+Rev+Drug+Discov 2017 ; 16 (3): 167-79 Nephropedia Template TP {{tp|p=27444227|t=2017. Perspectives: Noncoding RNAs as drug targets |pdf=|usr=}}{{27444227}} gab.com Text Perspectives: Noncoding RNAs as drug targets JO: Nat Rev Drug Discov http://www.kidney.de/pget.php?&tw=1&pmid=27444227 #FOAvip Most of the human genome encodes RNA that does not code for protein. These noncoding RNAs (ncRNAs) may affect normal gene expression and disease progression, making them a new class of targets for drug discovery. Because their mechanisms of action are often novel, developing drugs targeting ncRNAs will involve equally novel challenges. However, many potential problems may already have been solved during development of technologies to target mRNA. Here, we will discuss the growing field of ncRNA ? including microRNA, intronic RNA, repetitive RNA and long non-coding RNA - and assess the potential and challenges in their therapeutic exploitation. Twit Text FOAVip Perspectives: Noncoding RNAs as drug targets ????Nat Rev Drug Discov http://www.kidney.de/pget.php?&tw=1&pmid=27444227 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27444227 #FOAvip English Wikipedia <ref>{{Cite pmid|27444227}}</ref> Perspectives: Noncoding RNAs as drug targets #MMPMID27444227 Matsui M; Corey DR Nat Rev Drug Discov 2017[Mar]; 16 (3): 167-79 PMID27444227show ga Most of the human genome encodes RNA that does not code for protein. These noncoding RNAs (ncRNAs) may affect normal gene expression and disease progression, making them a new class of targets for drug discovery. Because their mechanisms of action are often novel, developing drugs targeting ncRNAs will involve equally novel challenges. However, many potential problems may already have been solved during development of technologies to target mRNA. Here, we will discuss the growing field of ncRNA ? including microRNA, intronic RNA, repetitive RNA and long non-coding RNA - and assess the potential and challenges in their therapeutic exploitation. äPerspectives: Noncoding RNAs as drug targets (epmc).pdf DeepDyve Pubget Overpricing