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10.1101/gad.306241.117 http://scihub22266oqcxt.onion/10.1101/gad.306241.117 C5830930!5830930!29440247     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+Dev 2018 ; 32 (2): 181-93 Nephropedia Template TP {{tp|p=29440247|t=2018. KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis |pdf=|usr=}}{{29440247}} gab.com Text KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis JO: Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=29440247 #FOAvip In this study, Lin-Shiao et al. identify a novel role for KMT2D, an epigenetic regulator, in coordinating self-renewal, proliferation, and differentiation, as depletion of KMT2D from undifferentiated epidermal keratinocytes results in reduced proliferation, premature spurious activation of terminal differentiation genes, and disorganized epidermal stratification. Their results reveal a critical role for KMT2D in the control of epithelial enhancers and p63 target gene expression, including the requirement of KMT2D for the maintenance of epithelial progenitor gene expression and the coordination of proper terminal differentiation. Twit Text FOAVip KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis ????Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=29440247 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29440247 #FOAvip English Wikipedia <ref>{{Cite pmid|29440247}}</ref> KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis #MMPMID29440247 Lin-Shiao E; Lan Y; Coradin M; Anderson A; Donahue G; Simpson CL; Sen P; Saffie R; Busino L; Garcia BA; Berger SL; Capell BC Genes Dev 2018[Jan]; 32 (2): 181-93 PMID29440247show ga In this study, Lin-Shiao et al. identify a novel role for KMT2D, an epigenetic regulator, in coordinating self-renewal, proliferation, and differentiation, as depletion of KMT2D from undifferentiated epidermal keratinocytes results in reduced proliferation, premature spurious activation of terminal differentiation genes, and disorganized epidermal stratification. Their results reveal a critical role for KMT2D in the control of epithelial enhancers and p63 target gene expression, including the requirement of KMT2D for the maintenance of epithelial progenitor gene expression and the coordination of proper terminal differentiation. äKMT2D regulates p63 target enhancers to coordinate epithelial homeosta(epmc).pdf DeepDyve Pubget Overpricing