Rare Cause of Hyperkalemia in the Newborn Period: Report of Two Cases of
Pseudohypoaldosteronism Type 1
#MMPMID29515305
Manipriya R
; Umamaheswari B
; Prakash A
; Binu N
Indian J Nephrol
2018[Jan]; 28
(1
): 69-72
PMID29515305
show ga
Pseudohypoaldosteronism (PHA) Type 1 is characterized by mineralocorticoid
resistance, manifesting as neonatal salt wasting, hypotension, hyperkalemia,
hyponatremia, and metabolic acidosis in spite of elevated aldosterone levels and
plasma renin activity. It is important to differentiate children with systemic
PHA from renal PHA, as these children are likely to decompensate even with mild
symptoms. Here, we report two neonates with PHA that presented to us with
multiorgan involvement.