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10.1155/2018/4020937 http://scihub22266oqcxt.onion/10.1155/2018/4020937 C5829322!5829322!29619127     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dis+Markers 2018 ; 2018 (ä): ä Nephropedia Template TP {{tp|p=29619127|t=2018. Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas |pdf=|usr=}}{{29619127}} gab.com Text Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas JO: Dis Markers http://www.kidney.de/pget.php?&tw=1&pmid=29619127 #FOAvip Background: Hu-antigen R (HuR) is a posttranscriptional regulator of several target mRNAs, implicated in carcinogenesis. This review aims to present the current evidence regarding the biological role and potential clinical significance of HuR in head and neck carcinomas. Methods: The existing literature concerning HuR expression and function in head and neck carcinomas is critically presented and summarised. Results: HuR is expressed in the majority of the examined samples, showing higher cytoplasmic levels in malignant or premalignant cases. Moreover, HuR modulates several genes implicated in biological processes important for malignant transformation, growth, and invasiveness. HuR seems to be an adverse prognosticator in patients with OSCCs, whereas a correlation with a more aggressive phenotype is reported in several types of carcinomas. Conclusions: A consistent role of HuR in the carcinogenesis and progression of head and neck carcinomas is suggested; nevertheless, further studies are warranted to expand the present information. Twit Text FOAVip Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas ????Dis Markers http://www.kidney.de/pget.php?&tw=1&pmid=29619127 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29619127 #FOAvip English Wikipedia <ref>{{Cite pmid|29619127}}</ref> Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas #MMPMID29619127 Levidou G; Kotta-Loizou I; Tasoulas J; Papadopoulos T; Theocharis S Dis Markers 2018[]; 2018 (ä): ä PMID29619127show ga Background: Hu-antigen R (HuR) is a posttranscriptional regulator of several target mRNAs, implicated in carcinogenesis. This review aims to present the current evidence regarding the biological role and potential clinical significance of HuR in head and neck carcinomas. Methods: The existing literature concerning HuR expression and function in head and neck carcinomas is critically presented and summarised. Results: HuR is expressed in the majority of the examined samples, showing higher cytoplasmic levels in malignant or premalignant cases. Moreover, HuR modulates several genes implicated in biological processes important for malignant transformation, growth, and invasiveness. HuR seems to be an adverse prognosticator in patients with OSCCs, whereas a correlation with a more aggressive phenotype is reported in several types of carcinomas. Conclusions: A consistent role of HuR in the carcinogenesis and progression of head and neck carcinomas is suggested; nevertheless, further studies are warranted to expand the present information. äClinical Significance and Biological Role of HuR in Head and Neck Carc(epmc).pdf DeepDyve Pubget Overpricing