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10.1002/advs.201700449 http://scihub22266oqcxt.onion/10.1002/advs.201700449 C5827100!5827100!29619297     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Adv+Sci+(Weinh) 2018 ; 5 (2): ä Nephropedia Template TP {{tp|p=29619297|t=2018. Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine |pdf=|usr=}}{{29619297}} gab.com Text Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine JO: Adv Sci (Weinh) http://www.kidney.de/pget.php?&tw=1&pmid=29619297 #FOAvip Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles consisting of a lipid bilayer enclosing proteins and nucleic acids, which are active in intercellular communications. EVs are increasingly seen as a vital component of many biological functions that were once considered to require the direct participation of stem cells. Consequently, transplantation of EVs is gradually becoming considered an alternative to stem cell transplantation due to their significant advantages, including their relatively low probability of neoplastic transformation and abnormal differentiation. However, as research has progressed, it is realized that EVs derived from native?source cells may have various shortcomings, which can be corrected by modification and optimization. To date, attempts are made to modify or improve almost all the components of EVs, including the lipid bilayer, proteins, and nucleic acids, launching a new era of modularized EV therapy through the ?modular design? of EV components. One high?yield technique, generating EV mimetic nanovesicles, will help to make industrial production of modularized EVs a reality. These modularized EVs have highly customized ?modular design? components related to biological function and targeted delivery and are proposed as a promising approach to achieve personalized and precision medicine. Twit Text FOAVip Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine ????Adv Sci (Weinh) http://www.kidney.de/pget.php?&tw=1&pmid=29619297 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29619297 #FOAvip English Wikipedia <ref>{{Cite pmid|29619297}}</ref> Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine #MMPMID29619297 Tao S; Guo S; Zhang C Adv Sci (Weinh) 2018[Feb]; 5 (2): ä PMID29619297show ga Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles consisting of a lipid bilayer enclosing proteins and nucleic acids, which are active in intercellular communications. EVs are increasingly seen as a vital component of many biological functions that were once considered to require the direct participation of stem cells. Consequently, transplantation of EVs is gradually becoming considered an alternative to stem cell transplantation due to their significant advantages, including their relatively low probability of neoplastic transformation and abnormal differentiation. However, as research has progressed, it is realized that EVs derived from native?source cells may have various shortcomings, which can be corrected by modification and optimization. To date, attempts are made to modify or improve almost all the components of EVs, including the lipid bilayer, proteins, and nucleic acids, launching a new era of modularized EV therapy through the ?modular design? of EV components. One high?yield technique, generating EV mimetic nanovesicles, will help to make industrial production of modularized EVs a reality. These modularized EVs have highly customized ?modular design? components related to biological function and targeted delivery and are proposed as a promising approach to achieve personalized and precision medicine. äModularized Extracellular Vesicles: The Dawn of Prospective Personaliz(epmc).pdf DeepDyve Pubget Overpricing