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10.1111/jcmm.13448 http://scihub22266oqcxt.onion/10.1111/jcmm.13448 C5824371!5824371!29193726     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29193726.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Cell+Mol+Med 2018 ; 22 (3): 2028-32 Nephropedia Template TP {{tp|p=29193726|t=2018. Dihydroartemisinin up?regulates VE?cadherin expression in human renal glomerular endothelial cells |pdf=|usr=}}{{29193726}} gab.com Text Dihydroartemisinin up regulates VE cadherin expression in human renal glomerular endothelial cells JO: J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=29193726 #FOAvip The antimalarial agent dihydroartemisinin (DHA) has been shown to be anti?inflammatory. In this study, we found that DHA increased the expression of the junctional protein vascular endothelial (VE)?cadherin in human renal glomerular endothelial cells. In addition, DHA inhibited TGF?? RI?Smad2/3 signalling and its downstream effectors SNAIL and SLUG, which repress VE?cadherin gene transcription. Correspondingly, DHA decreased the binding of SNAIL and SLUG to the VE?cadherin promoter. Together, our results suggest an effect of DHA in regulating glomerular permeability by elevation of VE?cadherin expression. Twit Text FOAVip Dihydroartemisinin up regulates VE cadherin expression in human renal glomerular endothelial cells ????J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=29193726 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29193726 #FOAvip English Wikipedia <ref>{{Cite pmid|29193726}}</ref> Dihydroartemisinin up?regulates VE?cadherin expression in human renal glomerular endothelial cells #MMPMID29193726 Li L; Chen X; Dong F; Liu Q; Zhang C; Xu D; Allen TD; Liu J J Cell Mol Med 2018[Mar]; 22 (3): 2028-32 PMID29193726show ga The antimalarial agent dihydroartemisinin (DHA) has been shown to be anti?inflammatory. In this study, we found that DHA increased the expression of the junctional protein vascular endothelial (VE)?cadherin in human renal glomerular endothelial cells. In addition, DHA inhibited TGF?? RI?Smad2/3 signalling and its downstream effectors SNAIL and SLUG, which repress VE?cadherin gene transcription. Correspondingly, DHA decreased the binding of SNAIL and SLUG to the VE?cadherin promoter. Together, our results suggest an effect of DHA in regulating glomerular permeability by elevation of VE?cadherin expression. äDihydroartemisinin up?regulates VE?cadherin expression in human renal (epmc).pdf DeepDyve Pubget Overpricing