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10.17925/EE.2016.12.01.44

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suck abstract from ncbi


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pmid29632589
      Eur+Endocrinol 2016 ; 12 (1 ): 44-46
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  • New Developments in the Treatment of Neuroendocrine Tumours - RADIANT-4, NETTER-1 and Telotristat Etiprate #MMPMID29632589
  • Sbardella E ; Grossman A
  • Eur Endocrinol 2016[Mar]; 12 (1 ): 44-46 PMID29632589 show ga
  • Neuroendocrine tumours (NETs) are a heterogeneous group of neoplasms whose incidence has increased significantly in recent years, and whose optimal management remains controversial. We report the latest innovations in their management, in particular the results of three trials concerning the use of the mammalian target of rapamycin (mTOR) inhibitor, everolimus, in non-functional NETs of lung/ gastrointestinal (GI) origin, the first randomised trial of radiolabelled (177)Lu-DOTATATE in patients with mid-gut NETs, and the use of the 5-HT synthesis inhibitor, telotristat etiprate, in patients with the carcinoid syndrome.
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