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10.17925/EE.2016.12.02.89 http://scihub22266oqcxt.onion/10.17925/EE.2016.12.02.89 C5813448!5813448!29632594     free     free     free       Eur+Endocrinol 2016 ; 12 (2): 89-95 Nephropedia Template TP {{tp|p=29632594|t=2016. Updates on Immune Therapies in Type 1 Diabetes |pdf=|usr=}}{{29632594}} gab.com Text Updates on Immune Therapies in Type 1 Diabetes JO: Eur Endocrinol http://www.kidney.de/pget.php?&tw=1&pmid=29632594 #FOAvip Multiple clinical trials investigating the efficacy and safety of immunotherapeutic interventions in new onset type 1 diabetes (T1D) have failed to yield long term clinical benefit. Lack of efficacy has frequently been attributed to an incomplete understanding of the pathways involved in T1D and the use of single immunotherapeutic agents. Recent mechanistic studies have improved our knowledge of the complex etiopathogenesis of T1D. This in turn has provided the framework for new and ongoing clinical trials in new onset T1D patients and at-risk subjects. Focus has also shifted towards the potential benefits of synergistic combinatorial approaches, both in terms of efficacy and the potential for reduced side effects. These efforts seek to develop intervention strategies that will preserve ?-cell function, and ultimately prevent and reverse clinical disease. Twit Text FOAVip Updates on Immune Therapies in Type 1 Diabetes ????Eur Endocrinol http://www.kidney.de/pget.php?&tw=1&pmid=29632594 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29632594 #FOAvip English Wikipedia <ref>{{Cite pmid|29632594}}</ref> Updates on Immune Therapies in Type 1 Diabetes #MMPMID29632594 Nambam B; Haller MJ Eur Endocrinol 2016[Aug]; 12 (2): 89-95 PMID29632594show ga Multiple clinical trials investigating the efficacy and safety of immunotherapeutic interventions in new onset type 1 diabetes (T1D) have failed to yield long term clinical benefit. Lack of efficacy has frequently been attributed to an incomplete understanding of the pathways involved in T1D and the use of single immunotherapeutic agents. Recent mechanistic studies have improved our knowledge of the complex etiopathogenesis of T1D. This in turn has provided the framework for new and ongoing clinical trials in new onset T1D patients and at-risk subjects. Focus has also shifted towards the potential benefits of synergistic combinatorial approaches, both in terms of efficacy and the potential for reduced side effects. These efforts seek to develop intervention strategies that will preserve ?-cell function, and ultimately prevent and reverse clinical disease. äUpdates on Immune Therapies in Type 1 Diabetes (epmc).pdf DeepDyve Pubget Overpricing