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10.15420/icr.2016.11.1.47

http://scihub22266oqcxt.onion/10.15420/icr.2016.11.1.47
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C5808707!5808707!29588705
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suck abstract from ncbi


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pmid29588705      Interv+Cardiol 2016 ; 11 (1): 47-50
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  • The use of the Cre8 Stent in Patients With Diabetes Mellitus #MMPMID29588705
  • Carrié D
  • Interv Cardiol 2016[May]; 11 (1): 47-50 PMID29588705show ga
  • Despite improved clinical outcomes following the availability of second-generation drug eluting stents (DES), percutaneous coronary intervention (PCI) is associated with worse clinical and angiographic outcomes among patients with diabetes mellitus (DM) than among non-diabetics. The Cre8? Amphilimus-eluting DES is polymer-free, resulting in a reduced inflammatory response and lower risk of stent thrombosis. It showed equivalent efficacy and safety in diabetic and non-diabetic populations, a unique finding among DES studies. These findings were confirmed in a real-world study called INVESTIG8. Another real-world study, pARTicip8, is ongoing. The RESERVOIR clinical trial recruited patients with diabetes mellitus and showed noninferiority of the Cre8 DES compared to an everolimus-eluting DES but showed a statistical superiority of Cre8 in diabetic patients with higher metabolic dysfunctions. The Cre8 DES is therefore a valuable option for this important patient population.
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