Safety and Efficacy of Protected Cardiac Intervention: Clinical Evidence for
Sentinel Cerebral Embolic Protection
#MMPMID29588741
Schäfer U
Interv Cardiol
2017[Sep]; 12
(2
): 128-132
PMID29588741
show ga
Stroke is a well-documented potential risk of structural cardiac interventions.
As a result of the far-reaching burden of stroke on patients, caregivers and the
healthcare system, new medical interventions and therapies are being developed to
help mitigate this risk. One such intervention is the recently FDA-cleared
Sentinel? Cerebral Protection System (Sentinel; Claret Medical, Santa Rosa, CA,
USA) designed to capture and remove debris dislodged during transcatheter aortic
valve replacement procedures. In the SENTINEL IDE Study, and in a more recent
all-comers trial, Sentinel significantly reduced periprocedural strokes by 63 and
70 % respectively. In this paper, we review the growing body of evidence
supporting the use of Sentinel in transcatheter aortic valve replacement and
other endovascular procedures.