Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/s41594-018-0022-z http://scihub22266oqcxt.onion/10.1038/s41594-018-0022-z C5805637!5805637!29379172     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Struct+Mol+Biol 2018 ; 25 (2): 163-9 Nephropedia Template TP {{tp|p=29379172|t=2018. Solution Structure and Elevator Mechanism of the Membrane Electron Transporter CcdA |pdf=|usr=}}{{29379172}} gab.com Text Solution Structure and Elevator Mechanism of the Membrane Electron Transporter CcdA JO: Nat Struct Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=29379172 #FOAvip Membrane oxidoredutase CcdA plays a central role in supplying reducing equivalents from the bacterial cytoplasm to the envelope. It transports electrons across the membrane using a single pair of cysteines by a mechanism which has not been elucidated. Here we report an NMR structure of the Thermus thermophilus CcdA (TtCcdA) in an oxidized and outward-facing state. CcdA consists of two inverted structural repeats of three transmembrane helices (2 × 3-TM). We computationally modeled and experimentally validated an inward-facing state, which suggests that CcdA uses an elevator-type movement to shuttle the reactive cysteines across the membrane. CcdA belongs to the LysE superfamily. Its structure may be relevant to other LysE clan transporters. Structure comparisons of CcdA, semiSWEET, Pnu, and major facilitator superfamily (MFS) transporters provide insights about membrane transporter architecture and mechanism. Twit Text FOAVip Solution Structure and Elevator Mechanism of the Membrane Electron Transporter CcdA ????Nat Struct Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=29379172 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29379172 #FOAvip English Wikipedia <ref>{{Cite pmid|29379172}}</ref> Solution Structure and Elevator Mechanism of the Membrane Electron Transporter CcdA #MMPMID29379172 Zhou Y; Bushweller JH Nat Struct Mol Biol 2018[Feb]; 25 (2): 163-9 PMID29379172show ga Membrane oxidoredutase CcdA plays a central role in supplying reducing equivalents from the bacterial cytoplasm to the envelope. It transports electrons across the membrane using a single pair of cysteines by a mechanism which has not been elucidated. Here we report an NMR structure of the Thermus thermophilus CcdA (TtCcdA) in an oxidized and outward-facing state. CcdA consists of two inverted structural repeats of three transmembrane helices (2 × 3-TM). We computationally modeled and experimentally validated an inward-facing state, which suggests that CcdA uses an elevator-type movement to shuttle the reactive cysteines across the membrane. CcdA belongs to the LysE superfamily. Its structure may be relevant to other LysE clan transporters. Structure comparisons of CcdA, semiSWEET, Pnu, and major facilitator superfamily (MFS) transporters provide insights about membrane transporter architecture and mechanism. äSolution Structure and Elevator Mechanism of the Membrane Electron Tra(epmc).pdf DeepDyve Pubget Overpricing