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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Mol+Biosyst 2017 ; 13 (8): 1432-7 Nephropedia Template TP
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C-Peptide Replacement Therapy in Type 1 Diabetes: Are We in the Trough of Disillusionment? #MMPMID28685788
Pinger C; Entwistle K; Bell T; Liu Y; Spence D
Mol Biosyst 2017[Jul]; 13 (8): 1432-7 PMID28685788show ga
Type 1 Diabetes is associated with such complications as blindness, kidney failure, and nerve damage. Replacing C-peptide, a hormone normally co-secreted with insulin, has been shown to reduce diabetes-related complications. Interestingly, after nearly 30 years of positive research results, C-peptide is still not being co-administered with insulin to diabetic patients. The following review discusses the potential of C-peptide as an auxilliary replacement therapy and why it's not currently being used as a therapeutic.