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10.12688/f1000research.12625.1 http://scihub22266oqcxt.onion/10.12688/f1000research.12625.1 C5795268!5795268!29744035     free     free     free       F1000Res 2018 ; 7 (ä): ä Nephropedia Template TP {{tp|p=29744035|t=2018. Human metapneumovirus - what we know now |pdf=|usr=}}{{29744035}} gab.com Text Human metapneumovirus - what we know now JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=29744035 #FOAvip Human metapneumovirus (HMPV) is a leading cause of acute respiratory infection, particularly in children, immunocompromised patients, and the elderly. HMPV, which is closely related to avian metapneumovirus subtype C, has circulated for at least 65 years, and nearly every child will be infected with HMPV by the age of 5. However, immunity is incomplete, and re-infections occur throughout adult life. Symptoms are similar to those of other respiratory viral infections, ranging from mild (cough, rhinorrhea, and fever) to more severe (bronchiolitis and pneumonia). The preferred method for diagnosis is reverse transcription-polymerase chain reaction as HMPV is difficult to culture. Although there have been many advances made in the past 16 years since its discovery, there are still no US Food and Drug Administration-approved antivirals or vaccines available to treat HMPV. Both small animal and non-human primate models have been established for the study of HMPV. This review will focus on the epidemiology, transmission, and clinical manifestations in humans as well as the animal models of HMPV pathogenesis and host immune response. Twit Text FOAVip Human metapneumovirus - what we know now ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=29744035 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29744035 #FOAvip English Wikipedia <ref>{{Cite pmid|29744035}}</ref> Human metapneumovirus - what we know now #MMPMID29744035 Shafagati N; Williams J F1000Res 2018[]; 7 (ä): ä PMID29744035show ga Human metapneumovirus (HMPV) is a leading cause of acute respiratory infection, particularly in children, immunocompromised patients, and the elderly. HMPV, which is closely related to avian metapneumovirus subtype C, has circulated for at least 65 years, and nearly every child will be infected with HMPV by the age of 5. However, immunity is incomplete, and re-infections occur throughout adult life. Symptoms are similar to those of other respiratory viral infections, ranging from mild (cough, rhinorrhea, and fever) to more severe (bronchiolitis and pneumonia). The preferred method for diagnosis is reverse transcription-polymerase chain reaction as HMPV is difficult to culture. Although there have been many advances made in the past 16 years since its discovery, there are still no US Food and Drug Administration-approved antivirals or vaccines available to treat HMPV. Both small animal and non-human primate models have been established for the study of HMPV. This review will focus on the epidemiology, transmission, and clinical manifestations in humans as well as the animal models of HMPV pathogenesis and host immune response. äHuman metapneumovirus - what we know now (epmc).pdf DeepDyve Pubget Overpricing