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10.1093/jnci/djw315 http://scihub22266oqcxt.onion/10.1093/jnci/djw315 C5756064!5756064!28376159     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Natl+Cancer+Inst 2017 ; 109 (4): ä Nephropedia Template TP {{tp|p=28376159|t=2017. Burdensome Research Procedures in Trials: Why Less Is More |pdf=|usr=}}{{28376159}} gab.com Text Burdensome Research Procedures in Trials: Why Less Is More JO: J Natl Cancer Inst http://www.kidney.de/pget.php?&tw=1&pmid=28376159 #FOAvip A large volume of trials involve invasive, nontherapeutic research procedures, like organ biopsy or sham surgeries, that can pose risks comparable with the experimental treatment itself but that have no direct benefit for volunteers. Though such procedures can enhance the value of clinical investigations, recent studies suggest that many studies involving invasive, nontherapeutic research procedures are not well planned and reported; some studies suggest that their results are often not utilized in the planning of new investigations. This commentary offers recommendations for how investigators, sponsors, and ethics committees might improve evaluation and implementation of studies involving invasive nontherapeutic procedures. We conclude by urging more demanding scientific standards for the rationale, design, and reporting of burdensome, nontherapeutic research procedures?particularly where they involve risk of serious complications. Twit Text FOAVip Burdensome Research Procedures in Trials: Why Less Is More ????J Natl Cancer Inst http://www.kidney.de/pget.php?&tw=1&pmid=28376159 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28376159 #FOAvip English Wikipedia <ref>{{Cite pmid|28376159}}</ref> Burdensome Research Procedures in Trials: Why Less Is More #MMPMID28376159 Kimmelman J; Resnik DB; Peppercorn J; Ratain MJ J Natl Cancer Inst 2017[Apr]; 109 (4): ä PMID28376159show ga A large volume of trials involve invasive, nontherapeutic research procedures, like organ biopsy or sham surgeries, that can pose risks comparable with the experimental treatment itself but that have no direct benefit for volunteers. Though such procedures can enhance the value of clinical investigations, recent studies suggest that many studies involving invasive, nontherapeutic research procedures are not well planned and reported; some studies suggest that their results are often not utilized in the planning of new investigations. This commentary offers recommendations for how investigators, sponsors, and ethics committees might improve evaluation and implementation of studies involving invasive nontherapeutic procedures. We conclude by urging more demanding scientific standards for the rationale, design, and reporting of burdensome, nontherapeutic research procedures?particularly where they involve risk of serious complications. äBurdensome Research Procedures in Trials: Why Less Is More (epmc).pdf DeepDyve Pubget Overpricing