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10.1084/jem.20160217

http://scihub22266oqcxt.onion/10.1084/jem.20160217
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C5748844!5748844!29203538
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suck abstract from ncbi


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pmid29203538      J+Exp+Med 2018 ; 215 (1): 303-18
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  • High mobility group box 1 orchestrates tissue regeneration via CXCR4 #MMPMID29203538
  • Tirone M; Tran NL; Ceriotti C; Gorzanelli A; Canepari M; Bottinelli R; Raucci A; Di Maggio S; Santiago C; Mellado M; Saclier M; François S; Careccia G; He M; De Marchis F; Conti V; Ben Larbi S; Cuvellier S; Casalgrandi M; Preti A; Chazaud B; Al-Abed Y; Messina G; Sitia G; Brunelli S; Bianchi ME; Vénéreau E
  • J Exp Med 2018[Jan]; 215 (1): 303-18 PMID29203538show ga
  • Inflammation and tissue regeneration follow tissue damage, but little is known about how these processes are coordinated. Tirone et al. show that alternative redox forms of high mobility group box 1 (HMGB1), the ?alarmin? signal released by damaged cells, trigger inflammation or tissue repair after injury by interacting with distinct receptors and that a nonoxidizable HMGB1 mutant promotes regeneration without exacerbating inflammation.
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