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10.1177/0018578717726517

http://scihub22266oqcxt.onion/10.1177/0018578717726517
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C5735711!5735711!29276275
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suck abstract from ncbi


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pmid29276275      Hosp+Pharm 2017 ; 52 (7): 469-70
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  • Chimeric Antigen Receptor T-Cell Therapy for Lymphomas #MMPMID29276275
  • Jolley B; Walker S
  • Hosp Pharm 2017[Jul]; 52 (7): 469-70 PMID29276275show ga
  • It is estimated that 2.1% of the population of the United States will develop non-Hodgkin lymphoma (NHL) in a lifetime. With treatment, 71% of patients with NHL live to 5 years. Because current drugs used for treatment do not cure all patients and cause serious adverse effects, new strategies have been studied to treat lymphoma. One new pharmacologic strategy is to use chimeric antigen receptor T-cell (CAR T-cell) therapy. CAR T-cell therapies are very potent. As a class, the CAR T-cell therapies have induced complete remission in 50% to 80% of patients. Most patients using CAR T-cell therapies develop cytokine release syndrome, with about 1 in 3 having a severe form of the syndrome. This article will briefly review CAR T-cell therapies in development.
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