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10.1002/jor.23627 http://scihub22266oqcxt.onion/10.1002/jor.23627 C5720932!5720932!28590060     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Orthop+Res 2018 ; 36 (1): 192-201 Nephropedia Template TP {{tp|p=28590060|t=2018. Structure?function relationships at the human spinal disc?vertebra interface |pdf=|usr=}}{{28590060}} gab.com Text Structure function relationships at the human spinal disc vertebra interface JO: J Orthop Res http://www.kidney.de/pget.php?&tw=1&pmid=28590060 #FOAvip Damage at the intervertebral disc?vertebra interface associates with back pain and disc herniation. However, the structural and biomechanical properties of the disc?vertebra interface remain underexplored. We sought to measure mechanical properties and failure mechanisms, quantify architectural features, and assess structure?function relationships at this vulnerable location. Vertebra?disc?vertebra specimens from human cadaver thoracic spines were scanned with micro?computed tomography (?CT), surface speckle?coated, and loaded to failure in uniaxial tension. Digital image correlation (DIC) was used to calculate local surface strains. Failure surfaces were scanned using scanning electron microscopy (SEM), and adjacent sagittal slices were analyzed with histology and SEM. Seventy?one percent of specimens failed initially at the cartilage endplate?bone interface of the inner annulus region. Histology and SEM both indicated a lack of structural integration between the cartilage endplate (CEP) and bone. The interface failure strength was increased in samples with higher trabecular bone volume fraction in the vertebral endplates. Furthermore, failure strength decreased with degeneration, and in discs with thicker CEPs. Our findings indicate that poor structural connectivity between the CEP and vertebra may explain the structural weakness at this region, and provide insight into structural features that may contribute to risk for disc?vertebra interface injury. The disc?vertebra interface is the site of failure in the majority of herniation injuries. Here we show new structure?function relationships at this interface that may motivate the development of diagnostics, prevention strategies, and treatments to improve the prognosis for many low back pain patients with disc?vertebra interface injuries. © 2017 The Authors. Journal of Orthopaedic Research® Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 36:192?201, 2018. Twit Text FOAVip Structure function relationships at the human spinal disc vertebra interface ????J Orthop Res http://www.kidney.de/pget.php?&tw=1&pmid=28590060 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28590060 #FOAvip English Wikipedia <ref>{{Cite pmid|28590060}}</ref> Structure?function relationships at the human spinal disc?vertebra interface #MMPMID28590060 Berg?Johansen B; Fields AJ; Liebenberg EC; Li A; Lotz JC J Orthop Res 2018[Jan]; 36 (1): 192-201 PMID28590060show ga Damage at the intervertebral disc?vertebra interface associates with back pain and disc herniation. However, the structural and biomechanical properties of the disc?vertebra interface remain underexplored. We sought to measure mechanical properties and failure mechanisms, quantify architectural features, and assess structure?function relationships at this vulnerable location. Vertebra?disc?vertebra specimens from human cadaver thoracic spines were scanned with micro?computed tomography (?CT), surface speckle?coated, and loaded to failure in uniaxial tension. Digital image correlation (DIC) was used to calculate local surface strains. Failure surfaces were scanned using scanning electron microscopy (SEM), and adjacent sagittal slices were analyzed with histology and SEM. Seventy?one percent of specimens failed initially at the cartilage endplate?bone interface of the inner annulus region. Histology and SEM both indicated a lack of structural integration between the cartilage endplate (CEP) and bone. The interface failure strength was increased in samples with higher trabecular bone volume fraction in the vertebral endplates. Furthermore, failure strength decreased with degeneration, and in discs with thicker CEPs. Our findings indicate that poor structural connectivity between the CEP and vertebra may explain the structural weakness at this region, and provide insight into structural features that may contribute to risk for disc?vertebra interface injury. The disc?vertebra interface is the site of failure in the majority of herniation injuries. Here we show new structure?function relationships at this interface that may motivate the development of diagnostics, prevention strategies, and treatments to improve the prognosis for many low back pain patients with disc?vertebra interface injuries. © 2017 The Authors. Journal of Orthopaedic Research® Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 36:192?201, 2018. äStructure?function relationships at the human spinal disc?vertebra int(epmc).pdf DeepDyve Pubget Overpricing