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10.3892/etm.2017.5123 http://scihub22266oqcxt.onion/10.3892/etm.2017.5123 C5704257!5704257 !29201225     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29201225 &cmd=llinks): Failed to open stream: HTTP request failed! 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Long non-coding RNA ANRIL promotes the proliferation, migration and invasion of human osteosarcoma cells |pdf=|usr=}}{{29201225 }} gab.com Text Long non-coding RNA ANRIL promotes the proliferation, migration and invasion of human osteosarcoma cells JO: Exp Ther Med http://www.kidney.de/pget.php?&tw=1&pmid=29201225 #FOAvip The long antisense non-coding RNA ANRIL is 3.8 kb in length and serves an important role in the tumorigenesis and progression of a number of malignancies. However, its function in human osteosarcoma remains unknown. The present study investigated the role of ANRIL in human osteosarcoma cell lines and clinical tumor samples. The expression of ANRIL was analyzed in 19 osteosarcoma and paired adjacent non-cancerous tissues using reverse transcription-quantitative polymerase chain reaction. Knockdown of ANRIL expression using lentivirus-mediated small interfering RNA was performed to investigate the role of ANRIL in tumor proliferation and metastasis using MTT, colony formation and transwell assays. The results demonstrated that ANRIL expression was upregulated in osteosarcoma tissues when compared with ANCT samples. In addition, knockdown of ANRIL expression in vitro reduced cell proliferation and invasion. These results indicated that ANRIL is upregulated in osteosarcoma tissues, and may promote the proliferation and metastasis of osteosarcoma cells. Therefore, ANRIL may serve as a novel biomarker and target of novel therapies for the treatment of patients with osteosarcoma. Twit Text FOAVip Long non-coding RNA ANRIL promotes the proliferation, migration and invasion of human osteosarcoma cells ????Exp Ther Med http://www.kidney.de/pget.php?&tw=1&pmid=29201225 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29201225 #FOAvip English Wikipedia <ref>{{Cite pmid|29201225 }}</ref> Long non-coding RNA ANRIL promotes the proliferation, migration and invasion of human osteosarcoma cells #MMPMID29201225 Cheng S ; Huang T ; Li P ; Zhang W ; Wang Z ; Chen Y Exp Ther Med 2017[Nov]; 14 (5 ): 5121-5125 PMID29201225 show ga The long antisense non-coding RNA ANRIL is 3.8 kb in length and serves an important role in the tumorigenesis and progression of a number of malignancies. However, its function in human osteosarcoma remains unknown. The present study investigated the role of ANRIL in human osteosarcoma cell lines and clinical tumor samples. The expression of ANRIL was analyzed in 19 osteosarcoma and paired adjacent non-cancerous tissues using reverse transcription-quantitative polymerase chain reaction. Knockdown of ANRIL expression using lentivirus-mediated small interfering RNA was performed to investigate the role of ANRIL in tumor proliferation and metastasis using MTT, colony formation and transwell assays. The results demonstrated that ANRIL expression was upregulated in osteosarcoma tissues when compared with ANCT samples. In addition, knockdown of ANRIL expression in vitro reduced cell proliferation and invasion. These results indicated that ANRIL is upregulated in osteosarcoma tissues, and may promote the proliferation and metastasis of osteosarcoma cells. Therefore, ANRIL may serve as a novel biomarker and target of novel therapies for the treatment of patients with osteosarcoma. äLong non-coding RNA ANRIL promotes the proliferation, migration and in(epmc).pdf DeepDyve Pubget Overpricing