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10.1002/rth2.12018 http://scihub22266oqcxt.onion/10.1002/rth2.12018 C5703432!5703432!29202121     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Res+Pract+Thromb+Haemost 2017 ; 1 (1): 33-40 Nephropedia Template TP {{tp|p=29202121|t=2017. Low level of the plasma sphingolipid, glucosylceramide, is associated with thrombotic diseases |pdf=|usr=}}{{29202121}} gab.com Text Low level of the plasma sphingolipid, glucosylceramide, is associated with thrombotic diseases JO: Res Pract Thromb Haemost http://www.kidney.de/pget.php?&tw=1&pmid=29202121 #FOAvip Essentials: Minor abundance plasma lipids, eg, glucosylceramide, can modulate blood coagulation reactionsThis lipid was measured in plasmas of 1 myocardial infarction and 2 venous thrombosis populationsLow plasma glucosylceramide levels were found in each population compared to matched controlsLow plasma glucosylceramide levels are associated with venous and arterial thrombosis Background: One previous pilot study suggested the association of low plasma glucosylceramide (GlcCer) levels with venous thrombosis (VTE) risk. Objective: We aimed to confirm and evaluate the association of low plasma GlcCer levels with VTE and myocardial infarction (MI) occurrence, respectively. Patients and Methods: We evaluated the association of GlcCer in two independent case?control studies of Caucasian VTE populations (N=210 and 636) and one case?control study of Caucasian MI patients (N=345). Result: Plasma GlcCer levels in VTE patients were lower compared to controls in two independent VTE populations (5.0 vs 5.8 ?g/mL, P=.003 for the Scripps registry, and 5.6 vs 6.0 ?g/mL, P=.001 for the Valencia registry, respectively). A low plasma GlcCer level (below tenth percentile of controls) was associated with increased VTE occurrence (odds ratio [OR]=3.7 [95% CI, 1.8?7.9] for Scripps registry and OR=2.1 [95% CI, 1.3?3.3] for Valencia registry, respectively). For the MI study, the median GlcCer plasma level was lower in MI patients than in controls (4.3 vs 5.6 ?g/mL, P<.001), and a low level of GlcCer (below tenth percentile of control) was associated with higher MI occurrence (OR=7.7, [95% CI, 4.3?13.8]). Conclusion: Lower concentration of GlcCer was associated with VTE occurrence in 2 independent studies and also with MI occurrence in 1 study. Twit Text FOAVip Low level of the plasma sphingolipid, glucosylceramide, is associated with thrombotic diseases ????Res Pract Thromb Haemost http://www.kidney.de/pget.php?&tw=1&pmid=29202121 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29202121 #FOAvip English Wikipedia <ref>{{Cite pmid|29202121}}</ref> Low level of the plasma sphingolipid, glucosylceramide, is associated with thrombotic diseases #MMPMID29202121 Deguchi H; Navarro S; Payne AB; Elias DJ; Dowling NF; Austin HD; Espaņa F; Medina P; Hooper WC; Griffin JH Res Pract Thromb Haemost 2017[Jul]; 1 (1): 33-40 PMID29202121show ga Essentials: Minor abundance plasma lipids, eg, glucosylceramide, can modulate blood coagulation reactionsThis lipid was measured in plasmas of 1 myocardial infarction and 2 venous thrombosis populationsLow plasma glucosylceramide levels were found in each population compared to matched controlsLow plasma glucosylceramide levels are associated with venous and arterial thrombosis Background: One previous pilot study suggested the association of low plasma glucosylceramide (GlcCer) levels with venous thrombosis (VTE) risk. Objective: We aimed to confirm and evaluate the association of low plasma GlcCer levels with VTE and myocardial infarction (MI) occurrence, respectively. Patients and Methods: We evaluated the association of GlcCer in two independent case?control studies of Caucasian VTE populations (N=210 and 636) and one case?control study of Caucasian MI patients (N=345). Result: Plasma GlcCer levels in VTE patients were lower compared to controls in two independent VTE populations (5.0 vs 5.8 ?g/mL, P=.003 for the Scripps registry, and 5.6 vs 6.0 ?g/mL, P=.001 for the Valencia registry, respectively). A low plasma GlcCer level (below tenth percentile of controls) was associated with increased VTE occurrence (odds ratio [OR]=3.7 [95% CI, 1.8?7.9] for Scripps registry and OR=2.1 [95% CI, 1.3?3.3] for Valencia registry, respectively). For the MI study, the median GlcCer plasma level was lower in MI patients than in controls (4.3 vs 5.6 ?g/mL, P<.001), and a low level of GlcCer (below tenth percentile of control) was associated with higher MI occurrence (OR=7.7, [95% CI, 4.3?13.8]). Conclusion: Lower concentration of GlcCer was associated with VTE occurrence in 2 independent studies and also with MI occurrence in 1 study. äLow level of the plasma sphingolipid, glucosylceramide, is associated (epmc).pdf DeepDyve Pubget Overpricing