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10.1073/pnas.1711673114 http://scihub22266oqcxt.onion/10.1073/pnas.1711673114 C5703306!5703306 !29114054     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29114054 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Proc+Natl+Acad+Sci+U+S+A 2017 ; 114 (47 ): 12590-12595 Nephropedia Template TP {{tp|p=29114054 |t=2017. Three-dimensional visualization and a deep-learning model reveal complex fungal parasite networks in behaviorally manipulated ants |pdf=|usr=}}{{29114054 }} gab.com Text Three-dimensional visualization and a deep-learning model reveal complex fungal parasite networks in behaviorally manipulated ants JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=29114054 #FOAvip Some microbes possess the ability to adaptively manipulate host behavior. To better understand how such microbial parasites control animal behavior, we examine the cell-level interactions between the species-specific fungal parasite Ophiocordyceps unilateralis sensu lato and its carpenter ant host (Camponotus castaneus) at a crucial moment in the parasite's lifecycle: when the manipulated host fixes itself permanently to a substrate by its mandibles. The fungus is known to secrete tissue-specific metabolites and cause changes in host gene expression as well as atrophy in the mandible muscles of its ant host, but it is unknown how the fungus coordinates these effects to manipulate its host's behavior. In this study, we combine techniques in serial block-face scanning-electron microscopy and deep-learning-based image segmentation algorithms to visualize the distribution, abundance, and interactions of this fungus inside the body of its manipulated host. Fungal cells were found throughout the host body but not in the brain, implying that behavioral control of the animal body by this microbe occurs peripherally. Additionally, fungal cells invaded host muscle fibers and joined together to form networks that encircled the muscles. These networks may represent a collective foraging behavior of this parasite, which may in turn facilitate host manipulation. Twit Text FOAVip Three-dimensional visualization and a deep-learning model reveal complex fungal parasite networks in behaviorally manipulated ants ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=29114054 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29114054 #FOAvip English Wikipedia <ref>{{Cite pmid|29114054 }}</ref> Three-dimensional visualization and a deep-learning model reveal complex fungal parasite networks in behaviorally manipulated ants #MMPMID29114054 Fredericksen MA ; Zhang Y ; Hazen ML ; Loreto RG ; Mangold CA ; Chen DZ ; Hughes DP Proc Natl Acad Sci U S A 2017[Nov]; 114 (47 ): 12590-12595 PMID29114054 show ga Some microbes possess the ability to adaptively manipulate host behavior. To better understand how such microbial parasites control animal behavior, we examine the cell-level interactions between the species-specific fungal parasite Ophiocordyceps unilateralis sensu lato and its carpenter ant host (Camponotus castaneus) at a crucial moment in the parasite's lifecycle: when the manipulated host fixes itself permanently to a substrate by its mandibles. The fungus is known to secrete tissue-specific metabolites and cause changes in host gene expression as well as atrophy in the mandible muscles of its ant host, but it is unknown how the fungus coordinates these effects to manipulate its host's behavior. In this study, we combine techniques in serial block-face scanning-electron microscopy and deep-learning-based image segmentation algorithms to visualize the distribution, abundance, and interactions of this fungus inside the body of its manipulated host. Fungal cells were found throughout the host body but not in the brain, implying that behavioral control of the animal body by this microbe occurs peripherally. Additionally, fungal cells invaded host muscle fibers and joined together to form networks that encircled the muscles. These networks may represent a collective foraging behavior of this parasite, which may in turn facilitate host manipulation. |*Host-Pathogen Interactions [MESH] |*Machine Learning [MESH] |Animals [MESH] |Ants/anatomy & histology/cytology/*microbiology [MESH] |Behavior, Animal [MESH] |Hypocreales/pathogenicity/physiology/*ultrastructure [MESH] |Image Processing, Computer-Assisted/statistics & numerical data [MESH] |Imaging, Three-Dimensional [MESH] |Mandible/microbiology [MESH]Three-dimensional visualization and a deep-learning model reveal compl(epmc).pdf DeepDyve Pubget Overpricing