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10.1080/19491034.2017.1337621 http://scihub22266oqcxt.onion/10.1080/19491034.2017.1337621 C5703262!5703262!28686487     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nucleus 2017 ; 8 (5): 506-14 Nephropedia Template TP {{tp|p=28686487|t=2017. Nanoscale invaginations of the nuclear envelope: Shedding new light on wormholes with elusive function |pdf=|usr=}}{{28686487}} gab.com Text Nanoscale invaginations of the nuclear envelope: Shedding new light on wormholes with elusive function JO: Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=28686487 #FOAvip Recent advances in fluorescence microscopy have opened up new possibilities to investigate chromosomal and nuclear 3D organization on the nanoscale. We here discuss their potential for elucidating topographical details of the nuclear lamina. Single molecule localization microscopy (SMLM) in combination with immunostainings of lamina proteins readily reveals tube-like invaginations with a diameter of 100?500 nm. Although these invaginations have been established as a frequent and general feature of interphase nuclei across different cell types, their formation mechanism and function have remained largely elusive. We critically review the current state of research, propose possible connections to lamina associated domains (LADs), and revisit the discussion about the potential role of these invaginations for accelerating mRNA nuclear export. Illustrative studies using 3D super-resolution imaging are shown and will be instrumental to decipher the physiological role of these nanoscale invaginations. Twit Text FOAVip Nanoscale invaginations of the nuclear envelope: Shedding new light on wormholes with elusive function ????Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=28686487 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28686487 #FOAvip English Wikipedia <ref>{{Cite pmid|28686487}}</ref> Nanoscale invaginations of the nuclear envelope: Shedding new light on wormholes with elusive function #MMPMID28686487 Schoen I; Aires L; Ries J; Vogel V Nucleus 2017[]; 8 (5): 506-14 PMID28686487show ga Recent advances in fluorescence microscopy have opened up new possibilities to investigate chromosomal and nuclear 3D organization on the nanoscale. We here discuss their potential for elucidating topographical details of the nuclear lamina. Single molecule localization microscopy (SMLM) in combination with immunostainings of lamina proteins readily reveals tube-like invaginations with a diameter of 100?500 nm. Although these invaginations have been established as a frequent and general feature of interphase nuclei across different cell types, their formation mechanism and function have remained largely elusive. We critically review the current state of research, propose possible connections to lamina associated domains (LADs), and revisit the discussion about the potential role of these invaginations for accelerating mRNA nuclear export. Illustrative studies using 3D super-resolution imaging are shown and will be instrumental to decipher the physiological role of these nanoscale invaginations. äNanoscale invaginations of the nuclear envelope: Shedding new light on(epmc).pdf DeepDyve Pubget Overpricing