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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Indian+J+Crit+Care+Med 2017 ; 21 (11): 802-3 Nephropedia Template TP
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Influenza B Virus Triggering Macrophage Activation Syndrome in an Infant #MMPMID29279647
Jayashree K; Rao S; Kamath N
Indian J Crit Care Med 2017[Nov]; 21 (11): 802-3 PMID29279647show ga
Macrophage activation syndrome (MAS) is a potentially fatal complication caused by excessive activation and expansion of macrophages and T lymphocytes. It can be triggered by various infections and is characterized by the development of cytopenias, hyperferritinemia, liver dysfunction, and coagulopathy. We report a 10-month-old female infant with fever, convulsions, and hepatosplenomegaly. Laboratory data of bicytopenia, low erythrocyte sedimentation rate, and elevated liver enzymes suggested MAS. This was supported by the presence of hyperferritinemia with hypertriglyceridemia. MAS was triggered by influenza B virus. She responded to treatment with immunoglobulin and steroid.