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10.1111/1471-0528.14400

http://scihub22266oqcxt.onion/10.1111/1471-0528.14400
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suck abstract from ncbi


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pmid27885772
      BJOG 2017 ; 124 (12 ): 1883-1890
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  • Clinical practice patterns on the use of magnesium sulphate for treatment of pre-eclampsia and eclampsia: a multi-country survey #MMPMID27885772
  • Long Q ; Oladapo OT ; Leathersich S ; Vogel JP ; Carroli G ; Lumbiganon P ; Qureshi Z ; Gülmezoglu AM
  • BJOG 2017[Nov]; 124 (12 ): 1883-1890 PMID27885772 show ga
  • OBJECTIVE: To characterise the current clinical practice patterns regarding the use of magnesium sulphate (MgSO(4) ) for eclampsia prevention and treatment in a multi-country network of health facilities and compare with international recommendations. DESIGN: Cross-sectional survey. SETTING: A total of 147 health facilities in 15 countries across Africa, Latin America and Asia. POPULATION: Heads of obstetric departments or maternity units. METHODS: Anonymous online and paper-based survey conducted in 2015. MAIN OUTCOME MEASURES: Availability and use of MgSO(4) ; availability of a formal clinical protocol for MgSO(4) administration; and MgSO(4) dosing regimens for eclampsia prevention and treatment. RESULTS: Magnesium sulphate and a formal protocol for its administration were reported to be always available in 87.4% and 86.4% of all facilities, respectively. MgSO(4) was used for the treatment of mild pre-eclampsia, severe pre-eclampsia and eclampsia in 24.3%, 93.5% and 96.4% of all facilities, respectively. Regarding the treatment of severe pre-eclampsia, 26.4% and 7.0% of all facilities reported using dosing regimens that were consistent with Zuspan and Pritchard regimens, respectively. Across regions, intramuscular maintenance regimens were more commonly used in the African region (45.7%) than in the Latin American (3.0%) and Asian (22.9%) regions, whereas intravenous maintenance regimens were more often used in the Latin American (94.0%) and Asian (60.0%) regions than in the African region (21.7%). Similar patterns were found for the treatment of eclampsia across regions. CONCLUSIONS: The reported clinical use of MgSO(4) for eclampsia prevention and treatment varied widely, and was largely inconsistent with current international recommendations. TWEETABLE ABSTRACT: MgSO(4) regimens for eclampsia prevention and treatment in many hospitals are inconsistent with international recommendations.
  • |Africa [MESH]
  • |Asia [MESH]
  • |Cross-Sectional Studies [MESH]
  • |Eclampsia/*drug therapy [MESH]
  • |Female [MESH]
  • |Health Facilities/*statistics & numerical data [MESH]
  • |Humans [MESH]
  • |Latin America [MESH]
  • |Magnesium Sulfate/*therapeutic use [MESH]
  • |Practice Patterns, Physicians'/*statistics & numerical data [MESH]
  • |Pre-Eclampsia/*drug therapy [MESH]
  • |Pregnancy [MESH]
  • |Surveys and Questionnaires [MESH]


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