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10.1007/s00232-017-9988-4 http://scihub22266oqcxt.onion/10.1007/s00232-017-9988-4 C5696491!5696491 !28914342     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28914342 &cmd=llinks): Failed to open stream: HTTP request failed! 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Quantification of the Intracellular Life Time of Water Molecules to Measure Transport Rates of Human Aquaglyceroporins |pdf=|usr=}}{{28914342 }} gab.com Text Quantification of the Intracellular Life Time of Water Molecules to Measure Transport Rates of Human Aquaglyceroporins JO: J Membr Biol http://www.kidney.de/pget.php?&tw=1&pmid=28914342 #FOAvip Orthodox aquaporins are transmembrane channel proteins that facilitate rapid diffusion of water, while aquaglyceroporins facilitate the diffusion of small uncharged molecules such as glycerol and arsenic trioxide. Aquaglyceroporins play important roles in human physiology, in particular for glycerol metabolism and arsenic detoxification. We have developed a unique system applying the strain of the yeast Pichia pastoris, where the endogenous aquaporins/aquaglyceroporins have been removed and human aquaglyceroporins AQP3, AQP7, and AQP9 are recombinantly expressed enabling comparative permeability measurements between the expressed proteins. Using a newly established Nuclear Magnetic Resonance approach based on measurement of the intracellular life time of water, we propose that human aquaglyceroporins are poor facilitators of water and that the water transport efficiency is similar to that of passive diffusion across native cell membranes. This is distinctly different from glycerol and arsenic trioxide, where high glycerol transport efficiency was recorded. Twit Text FOAVip Quantification of the Intracellular Life Time of Water Molecules to Measure Transport Rates of Human Aquaglyceroporins ????J Membr Biol http://www.kidney.de/pget.php?&tw=1&pmid=28914342 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28914342 #FOAvip English Wikipedia <ref>{{Cite pmid|28914342 }}</ref> Quantification of the Intracellular Life Time of Water Molecules to Measure Transport Rates of Human Aquaglyceroporins #MMPMID28914342 Palmgren M ; Hernebring M ; Eriksson S ; Elbing K ; Geijer C ; Lasi? S ; Dahl P ; Hansen JS ; Topgaard D ; Lindkvist-Petersson K J Membr Biol 2017[Dec]; 250 (6 ): 629-639 PMID28914342 show ga Orthodox aquaporins are transmembrane channel proteins that facilitate rapid diffusion of water, while aquaglyceroporins facilitate the diffusion of small uncharged molecules such as glycerol and arsenic trioxide. Aquaglyceroporins play important roles in human physiology, in particular for glycerol metabolism and arsenic detoxification. We have developed a unique system applying the strain of the yeast Pichia pastoris, where the endogenous aquaporins/aquaglyceroporins have been removed and human aquaglyceroporins AQP3, AQP7, and AQP9 are recombinantly expressed enabling comparative permeability measurements between the expressed proteins. Using a newly established Nuclear Magnetic Resonance approach based on measurement of the intracellular life time of water, we propose that human aquaglyceroporins are poor facilitators of water and that the water transport efficiency is similar to that of passive diffusion across native cell membranes. This is distinctly different from glycerol and arsenic trioxide, where high glycerol transport efficiency was recorded. |Aquaglyceroporins/*chemistry [MESH] |Humans [MESH] |Magnetic Resonance Spectroscopy [MESH]Quantification of the Intracellular Life Time of Water Molecules to Me(epmc).pdf DeepDyve Pubget Overpricing