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10.1128/IAI.00373-17 http://scihub22266oqcxt.onion/10.1128/IAI.00373-17 C5695122!5695122!28893915     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Infect+Immun 2017 ; 85 (12): ä Nephropedia Template TP {{tp|p=28893915|t=2017. Hyperbiofilm Formation by Bordetella pertussis Strains Correlates with Enhanced Virulence Traits |pdf=|usr=}}{{28893915}} gab.com Text Hyperbiofilm Formation by Bordetella pertussis Strains Correlates with Enhanced Virulence Traits JO: Infect Immun http://www.kidney.de/pget.php?&tw=1&pmid=28893915 #FOAvip Pertussis, or whooping cough, caused by the obligate human pathogen Bordetella pertussis is undergoing a worldwide resurgence. The majority of studies of this pathogen are conducted with laboratory-adapted strains which may not be representative of the species as a whole. Biofilm formation by B. pertussis plays an important role in pathogenesis. We conducted a side-by-side comparison of the biofilm-forming abilities of the prototype laboratory strains and the currently circulating isolates from two countries with different vaccination programs. Compared to the reference strain, all strains examined herein formed biofilms at high levels. Biofilm structural analyses revealed country-specific differences, with strains from the United States forming more structured biofilms. Bacterial hyperaggregation and reciprocal expression of biofilm-promoting and -inhibitory factors were observed in clinical isolates. An association of increased biofilm formation with augmented epithelial cell adhesion and higher levels of bacterial colonization in the mouse nose and trachea was detected. To our knowledge, this work links for the first time increased biofilm formation in bacteria with a colonization advantage in an animal model. We propose that the enhanced biofilm-forming capacity of currently circulating strains contributes to their persistence, transmission, and continued circulation. Twit Text FOAVip Hyperbiofilm Formation by Bordetella pertussis Strains Correlates with Enhanced Virulence Traits ????Infect Immun http://www.kidney.de/pget.php?&tw=1&pmid=28893915 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28893915 #FOAvip English Wikipedia <ref>{{Cite pmid|28893915}}</ref> Hyperbiofilm Formation by Bordetella pertussis Strains Correlates with Enhanced Virulence Traits #MMPMID28893915 Cattelan N; Jennings-Gee J; Dubey P; Yantorno OM; Deora R Infect Immun 2017[Dec]; 85 (12): ä PMID28893915show ga Pertussis, or whooping cough, caused by the obligate human pathogen Bordetella pertussis is undergoing a worldwide resurgence. The majority of studies of this pathogen are conducted with laboratory-adapted strains which may not be representative of the species as a whole. Biofilm formation by B. pertussis plays an important role in pathogenesis. We conducted a side-by-side comparison of the biofilm-forming abilities of the prototype laboratory strains and the currently circulating isolates from two countries with different vaccination programs. Compared to the reference strain, all strains examined herein formed biofilms at high levels. Biofilm structural analyses revealed country-specific differences, with strains from the United States forming more structured biofilms. Bacterial hyperaggregation and reciprocal expression of biofilm-promoting and -inhibitory factors were observed in clinical isolates. An association of increased biofilm formation with augmented epithelial cell adhesion and higher levels of bacterial colonization in the mouse nose and trachea was detected. To our knowledge, this work links for the first time increased biofilm formation in bacteria with a colonization advantage in an animal model. We propose that the enhanced biofilm-forming capacity of currently circulating strains contributes to their persistence, transmission, and continued circulation. äHyperbiofilm Formation by Bordetella pertussis Strains Correlates with(epmc).pdf DeepDyve Pubget Overpricing