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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Med+Case+Rep
2017 ; 11
(1
): 326
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Magnesium sulfate and ophthalmic artery Doppler velocimetry in patients with
severe preeclampsia: a case series
#MMPMID29151361
Oliveira CA
; Moreira de Sa RA
; Zamprogno KV
; Gutierrez da Matta F
; do Vale Araújo F
J Med Case Rep
2017[Nov]; 11
(1
): 326
PMID29151361
show ga
BACKGROUND: In the present study, we used Doppler velocimetry in the ophthalmic
artery to evaluate the hemodynamic status of the intracranial vasculature. This
is the first time in the literature that indices of ophthalmic artery Doppler
sonography of women with preeclampsia were evaluated before and after the use of
magnesium sulfate to prevent eclampsia. CASE PRESENTATION: Indices of ophthalmic
artery Doppler sonography of six women with severe preeclampsia at 27 to 33 weeks
of gestational age were evaluated before and after the use of magnesium sulfate
(10 minutes, 30 minutes, and 60 minutes after the magnesium sulfate loading
dosage. The patients' ages were 26 years (patient 01), 29 years (patient 02),
20 years (patient 03), 21 years (patient 04), 20 years (patient 05), and 19 years
(patient 06). The ethnic group of patients 01 and 04 was white and the ethnic
group of patients 02, 03, 05 and 06 was mulatto. CONCLUSIONS: The apparent
increase in resistance index and pulsatility index values, although there is no
statistical significance in this series of cases, and the decrease in peak ratio
values after the administration of magnesium sulfate reflect an increase in the
impedance to flow in the ophthalmic artery and consequently a reduction in
cerebral perfusion after the use of magnesium sulfate. This may explain how
magnesium sulfate protects women with severe preeclampsia against cerebral damage
and prevents acute convulsions in these patients. We believe that this case
series report may have a broader clinical impact across medicine because the
mechanism of how magnesium sulfate can protect patients and prevent acute
convulsions is controversial.