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10.1186/s13052-017-0422-4

http://scihub22266oqcxt.onion/10.1186/s13052-017-0422-4
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suck abstract from ncbi


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pmid29149860      Ital+J+Pediatr 2017 ; 43 (ä): ä
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  • Anaphylactic shock with methylprednisolone sodium succinate in a child with short bowel syndrome and cow?s milk allergy #MMPMID29149860
  • Porcaro F; Paglietti MG; Diamanti A; Petreschi F; Schiavino A; Negro V; Pecora V; Fiocchi A; Cutrera R
  • Ital J Pediatr 2017[]; 43 (ä): ä PMID29149860show ga
  • Background: Medications with methyl-prednisolone sodium succinate containing lactose, which potentially contains traces of cow?s milk proteins (CMP), could cause allergic reactions or compromise treatment of acute allergic reactions in sensitized patients. Case presentation: We describe the unusual case of a one-year-old child affected by short bowel syndrome and history of severe cow?s milk allergy (CMA) and anaphylactic reaction due to intravenous administration of methyl-prednisolone sodium succinate (Solu-Medrol 40 mg, Pfizer). He was admitted to our hospital for severe respiratory failure and was initially treated with methyl-prednisolone (Urbason 40 mg, Sanofi Aventis), then with methyl-prednisolone sodium succinate (Solu-Medrol 40 mg, Pfizer). After the intravenous administration of second steroid, immediate anaphylaxis was recorded and treatment was stopped. Antihistamine and epinephrine were required and symptom resolution occurred. Conclusion: Children who are highly sensitive to milk may have severe allergic reactions also after exposure to CMP through a different administration route than the oral one. Patients who have food allergies need to pay particular attention to the prescription of drugs and their formulation.
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