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10.1186/s13052-017-0422-4

http://scihub22266oqcxt.onion/10.1186/s13052-017-0422-4
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suck abstract from ncbi


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pmid29149860
      Ital+J+Pediatr 2017 ; 43 (1 ): 104
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  • Anaphylactic shock with methylprednisolone sodium succinate in a child with short bowel syndrome and cow s milk allergy #MMPMID29149860
  • Porcaro F ; Paglietti MG ; Diamanti A ; Petreschi F ; Schiavino A ; Negro V ; Pecora V ; Fiocchi A ; Cutrera R
  • Ital J Pediatr 2017[Nov]; 43 (1 ): 104 PMID29149860 show ga
  • BACKGROUND: Medications with methyl-prednisolone sodium succinate containing lactose, which potentially contains traces of cow's milk proteins (CMP), could cause allergic reactions or compromise treatment of acute allergic reactions in sensitized patients. CASE PRESENTATION: We describe the unusual case of a one-year-old child affected by short bowel syndrome and history of severe cow's milk allergy (CMA) and anaphylactic reaction due to intravenous administration of methyl-prednisolone sodium succinate (Solu-Medrol 40 mg, Pfizer). He was admitted to our hospital for severe respiratory failure and was initially treated with methyl-prednisolone (Urbason 40 mg, Sanofi Aventis), then with methyl-prednisolone sodium succinate (Solu-Medrol 40 mg, Pfizer). After the intravenous administration of second steroid, immediate anaphylaxis was recorded and treatment was stopped. Antihistamine and epinephrine were required and symptom resolution occurred. CONCLUSION: Children who are highly sensitive to milk may have severe allergic reactions also after exposure to CMP through a different administration route than the oral one. Patients who have food allergies need to pay particular attention to the prescription of drugs and their formulation.
  • |Anaphylaxis/*chemically induced/drug therapy/physiopathology [MESH]
  • |Animals [MESH]
  • |Cattle [MESH]
  • |Emergency Service, Hospital [MESH]
  • |Follow-Up Studies [MESH]
  • |Histamine Antagonists/therapeutic use [MESH]
  • |Humans [MESH]
  • |Infant [MESH]
  • |Injections, Intravenous [MESH]
  • |Male [MESH]
  • |Methylprednisolone Hemisuccinate/*adverse effects/therapeutic use [MESH]
  • |Milk Hypersensitivity/complications/*diagnosis [MESH]
  • |Respiratory Insufficiency/diagnosis/*drug therapy [MESH]
  • |Risk Assessment [MESH]
  • |Short Bowel Syndrome/complications/*diagnosis [MESH]


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