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10.1146/annurev-nutr-071812-161148 http://scihub22266oqcxt.onion/10.1146/annurev-nutr-071812-161148 C5693323!5693323!24850385     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Annu+Rev+Nutr 2014 ; 34 (ä): 31-55 Nephropedia Template TP {{tp|p=24850385|t=2014. AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole body levels |pdf=|usr=}}{{24850385}} gab.com Text AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole body levels JO: Annu Rev Nutr http://www.kidney.de/pget.php?&tw=1&pmid=24850385 #FOAvip The AMP-activated protein kinase (AMPK) signaling pathway arose early during evolution of eukaryotic cells, when it appears to have been involved in the response to glucose starvation and perhaps also in monitoring the output of the newly acquired mitochondria. Due to the advent of hormonal regulation of glucose homeostasis, glucose starvation is a less frequent event for mammalian cells than for single-celled eukaryotes. Nevertheless, the AMPK system has been preserved in mammals where, by monitoring cellular AMP:ATP and ADP:ATP ratios and balancing the rates of catabolism and ATP consumption, it maintains energy homeostasis at a cell-autonomous level. In addition, hormones involved in maintaining energy balance at the whole body level interact with AMPK in the hypothalamus. AMPK is activated by two widely used clinical drugs, metformin and aspirin, and also by many natural products of plants that are either derived from traditional medicines or are promoted as ?nutraceuticals?. Twit Text FOAVip AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole body levels ????Annu Rev Nutr http://www.kidney.de/pget.php?&tw=1&pmid=24850385 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24850385 #FOAvip English Wikipedia <ref>{{Cite pmid|24850385}}</ref> AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole body levels #MMPMID24850385 Hardie DG Annu Rev Nutr 2014[]; 34 (ä): 31-55 PMID24850385show ga The AMP-activated protein kinase (AMPK) signaling pathway arose early during evolution of eukaryotic cells, when it appears to have been involved in the response to glucose starvation and perhaps also in monitoring the output of the newly acquired mitochondria. Due to the advent of hormonal regulation of glucose homeostasis, glucose starvation is a less frequent event for mammalian cells than for single-celled eukaryotes. Nevertheless, the AMPK system has been preserved in mammals where, by monitoring cellular AMP:ATP and ADP:ATP ratios and balancing the rates of catabolism and ATP consumption, it maintains energy homeostasis at a cell-autonomous level. In addition, hormones involved in maintaining energy balance at the whole body level interact with AMPK in the hypothalamus. AMPK is activated by two widely used clinical drugs, metformin and aspirin, and also by many natural products of plants that are either derived from traditional medicines or are promoted as ?nutraceuticals?. äAMP-activated protein kinase: maintaining energy homeostasis at the ce(epmc).pdf DeepDyve Pubget Overpricing