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2017 ; 12
(11
): e0188057
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The associations between magnetic resonance imaging findings and low back pain: A
10-year longitudinal analysis
#MMPMID29141001
Tonosu J
; Oka H
; Higashikawa A
; Okazaki H
; Tanaka S
; Matsudaira K
PLoS One
2017[]; 12
(11
): e0188057
PMID29141001
show ga
PURPOSE: To conduct a 10-year longitudinal analysis of the relationship between
magnetic resonance imaging (MRI) findings and low back pain (LBP). MATERIALS AND
METHODS: Ninety-one volunteers with a history of LBP, but without current LBP
were recruited between 2005 and 2006. Participants' baseline demographics and MRI
findings were recorded. All volunteers were invited for a follow-up MRI in 2016;
of these, 49 volunteers (53.8%) participated in the follow-up. We enquired
whether they had LBP history during the 10 years between the baseline and
follow-up examinations. Sagittal T1 and T2-weighted MRI were used to assess the
intervertebral space from T12/L1 to L5/S1. We evaluated the presence of disc
degeneration by Pfirrmann's grading system, disc bulging, high intensity zone
(HIZ), spondylolisthesis, and any type of Modic changes in the follow-up MRIs. We
compared the follow-up MRI findings with the baseline findings; the progress of
each finding over the 10 years were also compared between the groups with (n =
36) and without (n = 13) LBP. RESULTS: Average age of the study participants at
follow-up was 44.8 years; 25 were female and 24 were male. Average age, sex, body
mass index, and smoking habits of those who did and did not participate in the
follow-up study, as well as the demographic characteristics of those who did and
did not have LBP history during the 10 years, were not significantly different.
Compared with the group without LBP history, the group that had LBP history
during the 10 years did not have a significantly increased prevalence of disc
degeneration, disc bulging, and HIZ in the follow-up and baseline MRIs.
Spondylolisthesis and any type of Modic changes were also not associated with LBP
history during the 10 years. CONCLUSIONS: Follow-up MRI findings consistent with
Pfirrmann grading ?4, disc bulging, HIZ, spondylolisthesis, and any type of Modic
changes were not associated with LBP history during the 10 years between the
baseline and follow-up study. The progresses of these findings were also not
associated with the LBP history. In addition, baseline MRI findings were not
associated with LBP history during the 10 years; therefore, our data suggest that
baseline MRI findings cannot predict future LBP.