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10.3389/fendo.2017.00311 http://scihub22266oqcxt.onion/10.3389/fendo.2017.00311 C5686046!5686046!29176962     free     free     free       Front+Endocrinol+(Lausanne) 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=29176962|t=2017. E2F1, a Novel Regulator of Metabolism |pdf=|usr=}}{{29176962}} gab.com Text E2F1, a Novel Regulator of Metabolism JO: Front Endocrinol (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=29176962 #FOAvip In the past years, several lines of evidence have shown that cell cycle regulatory proteins also can modulate metabolic processes. The transcription factor E2F1 is a central player involved in cell cycle progression, DNA-damage response, and apoptosis. Its crucial role in the control of cell fate has been extensively studied and reviewed before; however, here, we focus on the participation of E2F1 in the regulation of metabolism. We summarize recent findings about the cell cycle-independent roles of E2F1 in various tissues that contribute to global metabolic homeostasis and highlight that E2F1 activity is increased during obesity. Finally, coming back to the pivotal role of E2F1 in cancer development, we discuss how E2F1 links cell cycle progression with different metabolic adaptations required for cell growth and survival. Twit Text FOAVip E2F1, a Novel Regulator of Metabolism ????Front Endocrinol (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=29176962 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29176962 #FOAvip English Wikipedia <ref>{{Cite pmid|29176962}}</ref> E2F1, a Novel Regulator of Metabolism #MMPMID29176962 Denechaud PD; Fajas L; Giralt A Front Endocrinol (Lausanne) 2017[]; 8 (ä): ä PMID29176962show ga In the past years, several lines of evidence have shown that cell cycle regulatory proteins also can modulate metabolic processes. The transcription factor E2F1 is a central player involved in cell cycle progression, DNA-damage response, and apoptosis. Its crucial role in the control of cell fate has been extensively studied and reviewed before; however, here, we focus on the participation of E2F1 in the regulation of metabolism. We summarize recent findings about the cell cycle-independent roles of E2F1 in various tissues that contribute to global metabolic homeostasis and highlight that E2F1 activity is increased during obesity. Finally, coming back to the pivotal role of E2F1 in cancer development, we discuss how E2F1 links cell cycle progression with different metabolic adaptations required for cell growth and survival. äE2F1, a Novel Regulator of Metabolism (epmc).pdf DeepDyve Pubget Overpricing