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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Clin+Transl+Endocrinol 2014 ; 1 (4): 145-50 Nephropedia Template TP
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Optimizing insulin injection technique and its effect on blood glucose control* #MMPMID29159095
Grassi G; Scuntero P; Trepiccioni R; Marubbi F; Strauss K
J Clin Transl Endocrinol 2014[Dec]; 1 (4): 145-50 PMID29159095show ga
Purpose: The purpose of the study is to assess whether proper Injection Technique (IT) is associated with improved glucose control over a three month period. Methods: Patients (N = 346) with diabetes from 18 ambulatory centers throughout northern Italy who had been injecting insulin ? four years answered a questionnaire about their IT. The nurse then examined the patient's injection sites for the presence of lipohypertrophy (LH), followed by an individualized training session in which sub-optimal IT practices highlighted in the questionnaire were addressed. All patients were taught to rotate sites correctly to avoid LH and were begun on 4 mm pen needles to avoid intramuscular (IM) injections. They were instructed not to reuse needles. Results: Nearly 49% of patients were found to have LH at study entry. After three months, patients had mean reductions in HbA1c of 0.58% (0.50%?0.66%, 95% CI), in fasting blood glucose of 14 mg/dL (10.2?17.8 mg/dL, 95% CI) and in total daily insulin dose of 2.0 IU (1.4?2.5 IU, 95% CI) all with p < 0.05. Follow-up questionnaires showed significant numbers of patients recognized the importance of IT and were performing their injections more correctly. The majority found the 4 mm needle convenient and comfortable. Conclusions: Targeted individualized training in IT, including the switch to a 4 mm needle, is associated with improved glucose control, greater satisfaction with therapy, better and simpler injection practices and possibly lower consumption of insulin after only a three month period.